An optical fibre reflectance sensor for p-aminophenol determination based on tetrahydroxycalix[4]arene as sensing reagent

Filik, Hayati; Aksu, Duygu; Apak, Reşat; Şener, İzzet; Kılıç, Emine Zinnur

doi:10.1016/j.snb.2008.11.011

Cited by 38 publications

(25 citation statements)

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“…In the previous reports, some quinone products have been reported after oxidation of phenol and phenol derivates [21,22]. Other reports have indicated a quinoneimine product produced after PAP oxidation [2,23]. However, the reductive peak of 1 mM p-benzoquinone (dot line of Figure 1A) shows a similar potential around 0 V. We believe the two reductive peaks of PAP are resulting from reduction of quinonimine and its relative hydrolysis product, pbenzoquinone, respectively.…”

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confidence: 65%

“…The p-aminophenol (PAP) is a primary hydrolytic degradation product of acetaminophen (AC) [1], and AC is very widely used as analgesic and antipyretic drug to reduce fever, cough and cold. Moreover, p-aminophenol is very harmful for human body due to its structural similarity to aniline and phenol [2]. It is limited to a low level of 0.005% in the drug substance by the European Pharmacopoeia (Ph.…”

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confidence: 99%

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New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

et al. 2010

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New determination scheme of p-aminophenol by using MnO 2 as a preoxidant is demonstrated in this work. In the flow injection system, the p-aminophenol is oxidized to quinoneimine by MnO 2 at up-stream, which can be detected at a suitable reductive potential. After optimization, the linear range of PAP is started from 1 mM to 30 mM (R 2 ¼ 0.999), the estimated detection limit (S/N ¼ 3) is 0.28 mM. Two real samples are studied and excellent recoveries are achieved by using standard addition method. The p-aminophenol (PAP) is a primary hydrolytic degradation product of acetaminophen (AC) [1], and AC is very widely used as analgesic and antipyretic drug to reduce fever, cough and cold. Moreover, p-aminophenol is very harmful for human body due to its structural similarity to aniline and phenol [2]. It is limited to a low level of 0.005% in the drug substance by the European Pharmacopoeia (Ph. Eur.) [3]. The PAP or PAP derivate compounds are common pollutants in effluents from cooking oil refineries, production of pesticides and herbicides, dyes and textiles, pharmaceuticals, pulp and paper, plastics, and detergent [4], because they are extremely toxic to aquatic life and impart a strong disagreeable taste to water [5]. Several researches have reported different PAP determination schemes including high performance chromatography (HPLC), capillary electrophoresis (CE) [6 -10], optical chemical sensors [11,12] and electrochemical sensor [13 -15]. Among the aforementioned schemes, the advantages of electrochemical scheme are low cost and less time consuming. Other applications of PAP are used as electroactive polymer film [16,17] in the determination of the ascorbic acid. But the poly-PAP film only shows the electroactive property in acid condition. In the neutral or alkaline condition, it is well known, the poly-PAP is accumulated onto electrode surface leading to the electrode inactivation and the hindrance of signal in further electroanalytical measurements. Thus, the determination of PAP in neutral or alkaline condition is very hard to avoid the formation of nonconductive film on the electrode surface. Some electrode surface cleaning schemes [18 -20] or chemical modified electrodes [13 -15] have been reported to solve this problem. However, the aforementioned electrode cleaning schemes are not convenient for further application and the pulse cleaning scheme may damage the electrode surface either.In this work, the MnO 2 was modified on a dummied upstream electrode as a preoxidant to selective oxidation of the PAP. Subsequently, the oxidized product is detected by the down-stream electrode. This simple scheme avoids the polymerization effect of the PAP with direct oxidative method. Two surface water samples collected from local pond and field were adopted as real samples. The flow injection analysis (FIA) coupled with MnO 2 modified electrode is used in PAP determination without enzyme modification, complicated sample treatment procedures and expensive electrode materials.The solid line of Figure 1A shows a ...

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New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

et al. 2010

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“…Up to now, various techniques have been developed to determine 4-AP, such as spectrophotometry [4], HPLC [5], capillary electrophoresis [6] and optical fibre reflectance sensor [7]. And some satisfactory results have been obtained.…”

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confidence: 99%

Electrochemical behavior and voltammetric determination of 4-aminophenol based on graphene–chitosan composite film modified glassy carbon electrode

Yin

Zhou

et al. 2010

Electrochimica Acta

211

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“…The sensor design was similar to that described by Ahmad and Narayanaswamy and Filik et al [26][27][28][29]. The probe was built using disposable syringe tubes (Tyco Healthcare Group LP, Büyükçekmece, Istanbul, Turkey).…”

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confidence: 99%

Rapid Determination of Calcium in Milk and Water Samples by Reflectance Spectroscopy

Filik¹,

Aksu²,

Apak³

2011

AJAC

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Reflectance spectroscopy (RS) can be used as a rapid and sensitive method for the quantitative determination of low amounts of calcium. In this analytical technique, the analyte in complex samples is extracted onto a solid sorbent matrix loaded with glyoxal bis (2-hydroxyanil (GBHA) and then quantified directly on the sorbent surface. The measurements were carried out at a wavelength of 566.1 nm yielding the largest divergence of reflectance spectra before and after reaction with the analyte element. The optimum response was obtained in 0.2 mol⋅L -1 NaOH solution, and the response time of the sensor was about 5 min, depending on the concentration of Ca(II). The calibration curve of Ca(II) was found to be linear on semi-logarithmic scale within the concentration range of 0.3 -40 mg⋅L -1 , with a LOD of 0.15 mg⋅L -1 in the low concentration range. The sensor response from different sensors (n = 5) gave an R.S.D. of 1.4% at 10 mg⋅L -1 Ca(II). The response characteristics of the sensor including dynamic range, reversibility, reproducibility, response time and lifetime are discussed in detail. The main advantages of this prototype device are sensitivity and higher selectivity over Mg(II). The proposed method has been successfully applied to the determination of Ca(II) in milk and drinking water samples.

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An optical fibre reflectance sensor for p-aminophenol determination based on tetrahydroxycalix[4]arene as sensing reagent

Cited by 38 publications

References 33 publications

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

Electrochemical behavior and voltammetric determination of 4-aminophenol based on graphene–chitosan composite film modified glassy carbon electrode

Rapid Determination of Calcium in Milk and Water Samples by Reflectance Spectroscopy

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An optical fibre reflectance sensor for p-aminophenol determination based on tetrahydroxycalix[4]arene as sensing reagent

Cited by 38 publications

References 33 publications

New Determination Scheme of p‐Aminophenol by MnO2 Modified Electrode Coupled with Flow Injection Analysis

New Determination Scheme of p‐Aminophenol by MnO2 Modified Electrode Coupled with Flow Injection Analysis

Electrochemical behavior and voltammetric determination of 4-aminophenol based on graphene–chitosan composite film modified glassy carbon electrode

Rapid Determination of Calcium in Milk and Water Samples by Reflectance Spectroscopy

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New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis