Over the past few decades, due to environmental and economic factors, the sugarcane has been considered a versatile and important plant to the several countries. The energysugar-ethanol agro-industries are seeking to take advantage of all its material, with the main products produced being renewable energy, sugar and ethanol. In this chapter, we propose to present a review of the important works that use mathematical and computational tools, aiming to optimize the sugarcane harvesting, in the past 30 years.