An Oral Squamous Cell Carcinoma Based on a Chronic Denture Irritation

Abstract

Oral squamous cell carcinoma (OSCC), the sixth most-common head and neck neoplasm, constitutes more than 80% of all malignancies found in the oral cavity. 1 OSCC is usually seen in middle-aged and older individuals. Its prevelance in males is slightly higher than in females. Although it can occur in all sites of the oral cavity such as the mucosal sides of cheeks, lips or the palatal regions, the most common occurance area is the posterolateral ventral side of the tongue. 2 Consuming alcohol and tobacco, long-term ultraviolet exposure, radiation, malnutrition, poor oral hygene and chronic mechanic irritations (CMI) are the main risk factors of OSCC. CMI can originate from dental, prosthetic or functional factors and cause traumatic ulcerations. 3 Due to the fact that OSCC usually initially arises as an oral ulcer with indurated margins the detection of chronic ulcers during oral examination, is a very important issue to which clinicians should pay a great deal attention. Siegel et al. reported the lack of information about the early diagnosis of malignant neoplasia in elderly denture wearers. 4 In such patients, malignant lesions are often confused with simple

Investigation of the prevalence of potentially malignant and malignant oral lesions in the Southeastern Anatolia Region of Turkey: A 5-year retrospective study

“…In contrast, Zokaee et al reported an increased frequency of potentially malignant lesions on the tongue [9]. Although oral squamous cell carcinoma (OSCC) may develop on the cheeks, lips, or palate, the tongue is the most frequent location [24]. In this study, OSCC was most commonly observed in the lower lip and tongue.…”