An outbreak of calicivirus associated gastroenteritis in an elderly persons home. A possible zoonosis?

Humphrey, T. J.; Cruickshank, J. G.; Cubitt, W. D.

doi:10.1017/s0022172400064822

Cited by 34 publications

(24 citation statements)

References 9 publications

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“…1) (1). Sapovirus particles were first detected in human diarrheic stool samples in 1976 in the United Kingdom using electron microscopy (EM) (2), and the virus was soon recognized as a new gastroenteritis pathogen (3)(4)(5)(6)(7)(8)(9)(10)(11). However, the prototype strain of the Sapovirus genus was from another outbreak in Sapporo, Japan, in 1982 (strain Hu/SaV/Sapporo/1982/JPN), because it has been studied extensively for sapovirus virological and genetic characteristics (10,(12)(13)(14).…”

Section: Historymentioning

confidence: 99%

“…Based on the epidemiological data from patients with sapovirus gastroenteritis, the incubation period ranges from less than 1 day to 4 days (5,8,44,130,135,178,183,184). Major clinical symptoms include diarrhea and vomiting; however, additional constitutional symptoms (i.e., nausea, stomach/abdominal cramps, chills, headache, myalgia, or malaise) are also frequently reported.…”

Section: Symptoms and Severity Of Diseasementioning

confidence: 99%

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Comprehensive Review of Human Sapoviruses

et al. 2015

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SUMMARY Sapoviruses cause acute gastroenteritis in humans and animals. They belong to the genus Sapovirus within the family Caliciviridae . They infect and cause disease in humans of all ages, in both sporadic cases and outbreaks. The clinical symptoms of sapovirus gastroenteritis are indistinguishable from those caused by noroviruses, so laboratory diagnosis is essential to identify the pathogen. Sapoviruses are highly diverse genetically and antigenically. Currently, reverse transcription-PCR (RT-PCR) assays are widely used for sapovirus detection from clinical specimens due to their high sensitivity and broad reactivity as well as the lack of sensitive assays for antigen detection or cell culture systems for the detection of infectious viruses. Sapoviruses were first discovered in 1976 by electron microscopy in diarrheic samples of humans. To date, sapoviruses have also been detected from several animals: pigs, mink, dogs, sea lions, and bats. In this review, we focus on genomic and antigenic features, molecular typing/classification, detection methods, and clinical and epidemiological profiles of human sapoviruses.

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Section: Historymentioning

confidence: 99%

Section: Symptoms and Severity Of Diseasementioning

confidence: 99%

Comprehensive Review of Human Sapoviruses

et al. 2015

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“…12 Thus far, to our knowledge, no HuNoVs have been detected in pets, although several years ago a report suggested that a sick dog caused an NoV outbreak in a retirement home in the UK. 13 …”

Section: Introductionmentioning

confidence: 99%

Pet dogs—A transmission route for human noroviruses?

Summa¹,

Bonsdorff²,

Maunula³

2012

Journal of Clinical Virology

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“…Occasionally SaV outbreaks occur in the elderly in nursing homes Humphrey et al, 1984;Gray et al, 1987;Simor et al, 1990], but rarely in adults under 65 years of age, although an outbreak involving teachers in a school in the USA [Noel et al, 1997] and a nosocomial outbreak affecting adult patients and medical staff [Johansson et al, 2005] have been reported. Sporadic cases of SaV gastroenteritis in adults occur occasionally and have been reported in Japan [Okada et al, 2002] and the UK (this study).…”

Section: Introductionmentioning

confidence: 99%

Characterization of sapoviruses collected in the United Kingdom from 1989 to 2004

Gallimore¹,

Iturriza‐Gómara²,

Lewis³

et al. 2006

J. Med. Virol.

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A fecal archive containing 115 sapovirus (SaV) strains detected in samples collected from 15 outbreaks and 98 sporadic cases of gastroenteritis between 1989 and 2004 in the UK were characterized in order to determine the genomic diversity within SaV co-circulating in the human population. Strains were characterized by partial sequencing of the genes encoding the RNA-dependent RNA polymerase (RdRp) region and/or the polymerase/capsid (Pol/Cap) junction of the open reading frame (Orf) 1. Overall, SaV of genogroup I genotype 1 (GI 1) were the predominant strains circulating in the UK in each year between 1989 and 2004. During 2004, GII 1 was the predominant strain. These two SaV types accounted for 89.5% of the sporadic cases and outbreaks in the UK. The remaining cases were caused by six other SaV genotypes. On the basis of partial sequencing of the RdRp and capsid encoding genes of strains, which did not show sufficient homology to any of the currently recognized genotypes, we propose the inclusion of a presumptive fourth genotype within genogroup I (GI 4).

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An outbreak of calicivirus associated gastroenteritis in an elderly persons home. A possible zoonosis?

Cited by 34 publications

References 9 publications

Comprehensive Review of Human Sapoviruses

Comprehensive Review of Human Sapoviruses

Pet dogs—A transmission route for human noroviruses?

Characterization of sapoviruses collected in the United Kingdom from 1989 to 2004

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