An Outbreak of Canine Babesiosis in Aomori Prefecture

Itoh, Naoyuki; Higuchi, Seiichi; Ogasawara, Toshimi; Ogasawara, Atsuko; Kawamura, Seiichi

doi:10.12935/jvma1951.40.167

Cited by 7 publications

(4 citation statements)

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“…This finding is similar to that found in a study reported 17 years ago [13]. In addition, a significant proportion of Tosa dogs (29.8%) were carriers of B. gibsoni in Aomori Prefecture, Japan.…”

Section: Discussionsupporting

confidence: 91%

Incidence of Canine Babesia gibsoni Infection and Subclinical Infection among Tosa dogs in Aomori Prefecture, Japan

Matsuu

Kawabe

Koshida

et al. 2004

The Journal of Veterinary Medical Science

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ABSTRACT. To identify the incidence of Babesia gibsoni (B. gibsoni) in Aomori Prefecture, northeastern Japan, dogs with acute B. gibsoni infection were investigated at the Animal Teaching Hospital, Kitasato University, between April 2002 and March 2003. Eighteen dogs with acute B. gibsoni infection were recognized; they were all male dogs of the fighting dog breed Tosa. Their platelet counts were below normal and their packed cell volumes (PCVs) were at various levels. We collected blood samples from 141 Tosa dogs from Aomori Prefecture and used polymerase chain reaction assay to investigate the incidence of subclinical B. gibsoni infection. We also looked into the serological abnormalities associated with thrombocytopenia or anemia in subclinical infection. Forty-one of 87 dogs (47.1%) with histories of dog fighting, and one dog of 54 without a history of dog fighting were positive for B. gibsoni; that is, 42 of 141 dogs (29.8%) showed a positive result. The mean platelet counts of dogs with subclinical infection were significantly lower and levels of anti-platelet IgG were significantly higher than levels for dogs without infection. Anti-erythrocyte membrane IgG levels were significantly higher in dogs with subclinical infections, although mean PCVs were not significantly different. Tosa dogs from Aomori Prefecture, Japan, were highly infected with B. gibsoni subclinically and this pathogen might be successfully transmitted during dog fighting. Dogs with subclinical infections were at risk of chronic thrombocytopenia, which may be due to autoimmune mechanisms. KEY WORDS: anti-erythrocyte membrane IgG, anti-platelet IgG, Babesia gibsoni, Tosa dog.

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Section: Discussionsupporting

confidence: 91%

Incidence of Canine Babesia gibsoni Infection and Subclinical Infection among Tosa dogs in Aomori Prefecture, Japan

Matsuu

Kawabe

Koshida

et al. 2004

The Journal of Veterinary Medical Science

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“…In Japan, it is distributed mainly in the western part [3,4,7,8] and only a few epidemiological and clinical studies have been reported on canine B. gibsoni infection in eastern Japan. All of the confirmed cases of B. gibsoni infection in the eastern part of Japan were found among Tosa dogs, a fighting breed raised only in Aomori Prefecture [3,10,17]. Transmission of B. gibsoni in this area was thought not to occur via ticks [3], although the vector tick species, Haemaphysalis longicornis, is distributed throughout Japan [19].…”

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confidence: 99%

Epidemiological Survey of Babesia gibsoni Infection in Dogs in Eastern Japan

Miyama

Sakata²,

Shimada

et al. 2005

J. Vet. Med. Sci.

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ABSTRACT. To determine the distribution of Babesia gibsoni infection in dogs in the eastern part of Japan, an epidemiological survey of dogs suspected of having B. gibsoni infection was attempted using the polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA). Thirty-five of 115 such dogs (30.4%) were positive by PCR and/or ELISA. The 35 positive dogs consisted of 28 Tosa dogs, 4 American Pit Bull Terriers, and 3 mongrel dogs in Aomori, Fukushima, Ibaraki, Gunma, Chiba, Tokyo, Kanagawa, and Nagano Prefectures. The positive dogs had a significantly lower rate of tick exposure and a higher rate of bites by other dogs. Twentytwo of 35 B. gibsoni-positive dogs were infected with hemoplasma, and the rate of infection was significantly higher than that of B. gibsoni-negative dogs.

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“…They were maintained in the laboratory by feeding on rabbits for several generations. The strain of B. gibsoni used was originally was isolated from naturally infected dogs in the Towada area in Aomori Prefecture, and maintained in the laboratory by passage through dogs [3]. Five splenectomized mongrel dogs, 9 to 12 months old, were used for transmission of the parasite.…”

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confidence: 99%

Development of Babesia gibsoni in the Midgut of Larval Tick, Rhipicephalus sanguineus.

Higuchi

Izumitani

Hoshi

et al. 1999

The Journal of Veterinary Medical Science

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ABSTRACT. Studies were made on the development of Babesia gibsoni in the midgut of the larval tick, Rhipicephalus sanguineus. Six hr after repletion, merozoites of B. gibsoni, freed from erythrocytes, were observed in the midgut contents of the tick. After that, within 24 hr, those merozoites were transformed into the ring-forms which were relatively large, 2-3 µm in diameter. Later, the ring forms developed into the spherical forms which were subelliptical in shape and 4-6 µm in diameter. Within 2-4 days, the elongated forms, 5-8 µm in length, were found. At this time, some of the binucleated fusion form has assumed a form intermediate between the spherical and elongated-forms. About 5-6 days after repletion, large round or elliptic zygotes, 8-10 µm in diameter, were observed in the tick gut.-KEY WORDS: Babesia gibsoni, development , Rhipicephalus sanguineus.

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An Outbreak of Canine Babesiosis in Aomori Prefecture

Cited by 7 publications

References 0 publications

Incidence of Canine Babesia gibsoni Infection and Subclinical Infection among Tosa dogs in Aomori Prefecture, Japan

Incidence of Canine Babesia gibsoni Infection and Subclinical Infection among Tosa dogs in Aomori Prefecture, Japan

Epidemiological Survey of Babesia gibsoni Infection in Dogs in Eastern Japan

Development of Babesia gibsoni in the Midgut of Larval Tick, Rhipicephalus sanguineus.

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