“…25 These studies do show wide variation in the cost impact of an outbreak due in part to the wide variety in scope, size, and number of outbreaks but also due to variability in the types of cost included (e.g., interventions, attributable sick leave for staff and overtime salary, cleaning expenses, diagnosis costs), costs of various items and services, and reimbursement policies. Weaknesses of these studies include the generalizablity, as they are specific to the outbreak hospital, some focus only on extra costs and lost revenue, [23][24][25] used a case definition of symptoms only, 22 and small sample size. 24 Modeling studies, which may overcome some of these limitations, estimate a case of norovirus to the hospital is an average $6237 26 and provide cost estimates for outbreaks of various sizes in differing size hospital wards.…”