An outbreak of peste des petits ruminants in a zoological collection

Abstract

Peste des petits ruminants virus was suspected to be the cause of a disease outbreak in a zoological collection at Al Ain in the Arabian Gulf. Clinically the outbreak affected gazelles (Gazellinae), ibex and sheep (Caprinae) and gemsbok (Hippotraginae); subclinical involvement of Nilgai (Tragelaphinae) was suspected. A morbillivirus was isolated and using monoclonal antibodies and biological tests in cattle, sheep and goats the virus of peste des petits ruminants was identified.

Diagnosis and control of peste des petits ruminants: a comprehensive review

“…Virus isolation cannot always be done as routine diagnostic assays because they are time-consuming and cumbersome and require cell culture facilities, and they are not as sensitive as RT-PCR [27]. VNT was performed for confirmation and differentiation of RP and PPR viruses [55,78], either in tubes or in microtitre plates (micro-VNT) for the detection of PPRV antibodies in serum samples [116,149]. Differential neutralization test is one of the important means to distinguish RP and PPR viruses [116,149] and a micro-VNT has been employed to measure the infectivity titre of RPV and PPRV in calf kidney, sheep kidney and Vero cells [116].…”

Epidemiological Analysis of Peste des Petits Ruminants (PPR) Outbreaks in Pakistan

“…Peste des Petits Ruminants (PPR) is an "acute, highly contagious and frequently fatal viral disease of sheep, goats and wild small ruminants" [1]. It is characterized by fever, muco-purulent ocular and nasal discharges, necrotizing and erosive stomatitis, severe enteritis and pneumonia leading to death [2].…”

Seroprevalance of Peste des Petits Ruminants (PPR) in Goitered Gazelle (Gazella subgutturosa subgutturosa) in Turkey

“…Cattle and pigs are generally recognized as dead-end hosts. Gazelles have a high susceptibility to PPRV infection (Furley et al, 1987). There are no data for PPR in goitered gazelles, but fatal peracute epidemics with 51% morbidity and 100% mortality have been reported in gazelle dorcas in Saudi Arabia (Abu Elzein et al, 2004).…”

“…Our data confirm the presence of natural infection of goitered gazelles with PPRV. Restriction of their current range seems not to be a means of definite protection, but antibody prevalence is not higher compared to other gazelle species (Furley et al, 1987;Abu Elzein et al, 2004). Because the location of the farm where this study was conducted included natural habitat of gazelles, the low morbidity might be explained by host-virus coadaptation.…”

“…Aside from sheep and goats, PPRV infection can pose potential health risks for many ruminant species and produce a range of symptoms from subclinical to fatal disorders (Furley et al, 1987;Ogunsanmi et al, 2003;Abu Elzein et al, 2004). Cattle and pigs are generally recognized as dead-end hosts.…”