The article describes a clinical case of drug resistant miliary tuberculosis in an immunocompetent woman with a multifetal pregnancy after in vitro fertilization (IVF). Difficulties in diagnosing miliary tuberculosis were due to the late detection of the initial focus of infection, that was endometrial tuberculosis, which generalized after IVF. The rare association of isthmic nodose salpingitis and a borderline ovarian tumor (serous ovarian cystadenoma) was a factor complicating the detection of tuberculosis.Conclusion: In an IVF program with bilateral fallopian tube occlusion, tuberculosis should be considered as a possible cause of this pathology. Endometrial tuberculosis is associated with a risk of repeated implantation failure and generalization of the disease.