An overview of addiction to sugar

Onaolapo, Adejoke Yetunde; Onaolapo, Olakunle James; Olowe, Olugbenga Adekunle

doi:10.1016/b978-0-12-816918-6.00009-3

Cited by 8 publications

(3 citation statements)

References 120 publications

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“…Additionally, the thermal treatment caused the beverage intake in these groups to be higher. This could be due to the release of neuroadapters in the reward system, which separates eating behavior from the homeostatic signaling of the hypothalamus (caloric), leading to compulsive eating [31,32]. Thus, the calories of solid foods are reduced to compensate for the calories of liquids generated in a diet [33].…”

Section: Discussionmentioning

confidence: 99%

Thermal Treatment of Commercial Sweetener Solutions Modulates the Metabolic Responses in C57BL/6 Mice during a 24-Week-Long Exposition

et al. 2023

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The purpose of this paper was to evaluate the effect of thermal treatment (TT: 121 ± 2 °C, 15 min) on the composition of commercial sweeteners diluted in water (10 °Brix). Additionally, we evaluated the impact of this TT on metabolic responses in C57BL/6 mice during a 24-week treatment. The sweeteners included in this study were sucrose (SC), glucose-63 (GLU63), agave syrup (AS), sucralose (SUC), and steviol glycosides (STG). HPLC analysis showed changes in the concentration of simple sugars of GLU63 and AS after TT. Importantly, in all sweeteners, TT modulated metabolic responses in mice. The mice drinking thermally treated sweetener solution showed an increase of 10–13% (p < 0.05) in food intake (AS, SUC, and STG), beverage intake (2–21%; SC and GLU63), weight gain (38%; SUC), energy (10–13%; AS, SUC, and STG), glucose levels (11–17%; SC and STG), GLP-1 (30%; SC) and insulin (88%; AS) release, and the generation of protein carbonyl (SC) and malondialdehyde (all sweeteners tested) compared to mice drinking solution without TT. In conclusion, TT of sweetener solutions accentuates the metabolic responses of healthy mice, which can be related to overweight and its comorbidities.

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Section: Discussionmentioning

confidence: 99%

Thermal Treatment of Commercial Sweetener Solutions Modulates the Metabolic Responses in C57BL/6 Mice during a 24-Week-Long Exposition

et al. 2023

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“…In contrast, free sugars such as disaccharides and monosaccharides (such as glucose and fructose) are frequently added to food and do not occur naturally. On the other hand, consuming too much energy is linked to the buildup of body fat (Onaolapo et al, 2020). More precisely, an excessive intake of free sugars increases the chance of developing other harmful health disorders, such as diabetes and cardiovascular illnesses, and reduces micronutrient density (Hagger et al, 2017).…”

Section: Adverse Effects Of Artificial Sugarsmentioning

confidence: 99%

Application of natural preservatives and sweeteners in fruit products to reduce health risks - a review

Valliath,

Johar,

Mondal

et al. 2023

ECJ

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The costs of food deterioration in terms of both money and health are rising. Fungi, bacteria, yeast, insects, and rodent contamination of food supplies continue to be a major public health concern. Chemical preservatives are effective but can be potentially fatal to human health in certain cases. As potent food preservatives, essential oils made from plants are a great alternative to synthetic preservatives. They also possess a variety of anti-inflammatory, antibacterial, and antioxidant effects. The use of artificial sweeteners in food products, which raises safety questions and health issues while also having reduced nutritional value, is another problem in the food industry. Because natural sweeteners are linked to a healthy lifestyle and have superior nutritional qualities, consumers today prefer them. This article goes through the issues with artificial sweeteners and preservatives and goes into great length about the many different essential oils and natural sweeteners that are much safer and healthier alternatives.

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“…It should also be indicated that the consumption of sugar or HSD can be addictive [ 189 , 190 ] and can predispose individuals to the risk of food addiction. At the neurochemical level, in both animals and humans there are significant similarities and overlaps between drugs of abuse and sugar, from brain neurochemistry to behaviour [ 189 ].…”

Section: Hsd As a Risk Factor To Develop Sud And Food Addictionmentioning

confidence: 99%

A High-Sugar Diet Consumption, Metabolism and Health Impacts with a Focus on the Development of Substance Use Disorder: A Narrative Review

2022

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Carbohydrates are important macronutrients in human and rodent diet patterns that play a key role in crucial metabolic pathways and provide the necessary energy for proper body functioning. Sugar homeostasis and intake require complex hormonal and nervous control to proper body energy balance. Added sugar in processed food results in metabolic, cardiovascular, and nervous disorders. Epidemiological reports have shown enhanced consumption of sweet products in children and adults, especially in reproductive age and in pregnant women, which can lead to the susceptibility of offspring’s health to diseases in early life or in adulthood and proneness to mental disorders. In this review, we discuss the impacts of high-sugar diet (HSD) or sugar intake during the perinatal and/or postnatal periods on neural and behavioural disturbances as well as on the development of substance use disorder (SUD). Since several emotional behavioural disturbances are recognized as predictors of SUD, we also present how HSD enhances impulsive behaviour, stress, anxiety and depression. Apart from the influence of HSD on these mood disturbances, added sugar can render food addiction. Both food and addictive substances change the sensitivity of the brain rewarding neurotransmission signalling. The results of the collected studies could be important in assessing sugar intake, especially via maternal dietary patterns, from the clinical perspective of SUD prevention or pre-existing emotional disorders. Methodology: This narrative review focuses on the roles of a high-sugar diet (HSD) and added sugar in foods and on the impacts of glucose and fructose on the development of substance use disorder (SUD) and on the behavioural predictors of drugs abuse. The literature was reviewed by two authors independently according to the topic of the review. We searched the PubMed and Scopus databases and Multidisciplinary Digital Publishing Institute open access scientific journals using the following keyword search strategy depending on the theme of the chapter: “high-sugar diet” OR “high-carbohydrate diet” OR “sugar” OR “glucose” OR “fructose” OR “added sugar” AND keywords. We excluded inaccessible or pay-walled articles, abstracts, conference papers, editorials, letters, commentary, and short notes. Reviews, experimental studies, and epidemiological data, published since 1990s, were searched and collected depending on the chapter structure. After the search, all duplicates are thrown out and full texts were read, and findings were rescreened. After the selection process, appropriate papers were included to present in this review.

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An overview of addiction to sugar

Cited by 8 publications

References 120 publications

Thermal Treatment of Commercial Sweetener Solutions Modulates the Metabolic Responses in C57BL/6 Mice during a 24-Week-Long Exposition

Thermal Treatment of Commercial Sweetener Solutions Modulates the Metabolic Responses in C57BL/6 Mice during a 24-Week-Long Exposition

Application of natural preservatives and sweeteners in fruit products to reduce health risks - a review

A High-Sugar Diet Consumption, Metabolism and Health Impacts with a Focus on the Development of Substance Use Disorder: A Narrative Review

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