Effects of Persistent and Bioactive Organic Pollutants on Human Health 2013
DOI: 10.1002/9781118679654.ch10
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An Overview of the Effects of Organic Compounds on Women's Reproductive Health and Birth Outcomes

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“…There is also evidence that maternal exposure to benzene, a hydrocarbon, can initiate childhood leukemia while the child is still in the uterus (Carlos-Wallace et al, 2016). Even in the absence of maternal exposure during pregnancy, fetal development may be a↵ected as harmful substances accumulate in maternal fat tissue before conception and are released during pregnancy (Reutman and Meadows, 2013). Second, the higher rates of spontaneous abortion associated with paternal exposure to hydrocarbons might result from higher rates of abnormal sperm characteristics (Celis et al, 2000).…”
Section: Evidence From Epidemiological and Clinical Researchmentioning
confidence: 99%
“…There is also evidence that maternal exposure to benzene, a hydrocarbon, can initiate childhood leukemia while the child is still in the uterus (Carlos-Wallace et al, 2016). Even in the absence of maternal exposure during pregnancy, fetal development may be a↵ected as harmful substances accumulate in maternal fat tissue before conception and are released during pregnancy (Reutman and Meadows, 2013). Second, the higher rates of spontaneous abortion associated with paternal exposure to hydrocarbons might result from higher rates of abnormal sperm characteristics (Celis et al, 2000).…”
Section: Evidence From Epidemiological and Clinical Researchmentioning
confidence: 99%
“…Coincidentally the decline in fertility in the AI/AN population coincides temporally with the rise of the obesity epidemic nationally. In addition, certain toxicants are known to affect the reproductive system including lead, DDT (DDE), and PCBs (Denham et al 2005; Reutmann and Meadows 2013; Selevan, et al 2003). While high PCB serum levels in women have been shown to lengthen menstrual cycle length (Cooper et al 2005), even low concentrations of p,p′-DDE and HCB have been positively correlated with failed fertility in women (Younglei et al 2002), and the induction of anovulatory cycles as well as the suppression of estradiol levels in non-human primates (Muller et al 1978) respectively.…”
Section: Discussionmentioning
confidence: 99%