In this study, we utilize a specific combination of orthogonal Gegenbauer polynomials as basis functions that satisfy homogeneous boundary conditions in the spatial variable and homogeneous initial conditions in the temporal variable. We derive an expression for the fractional derivative of the temporal basis and another expression for the second‐order derivative of the spatial basis. Subsequently, we discretize the nonlinear Fisher problem using the spectral collocation method to transform the problem into the solution of a nonlinear system of algebraic equations. We then solve this resulting system using Newton's method with an initial guess approaching zero. Furthermore, we conduct an error analysis of the proposed method and assess its applicability through three test problems, providing comparisons for validation.