An RCT: Use of Oxytocin Drip during Hysteroscopic Endometrial Resection and Its Effect on Operative Blood Loss and Glycine Deficit

Effect of oxytocin infusion on reducing the blood loss during abdominal myomectomy: a double‐blind randomised controlled trial

“…However, these strategies may be associated with some complications, and some of these are ineffective or expensive or required extra steps before the actual procedure. [20][21][22] Myomectomy is an operation where significant haemorrhage can occur. Its main function is uterine contraction during labour and delivery.…”

Safety and efficacy of manual syringe infusion of distending media for hysteroscopic procedures: a case–control study

“…However, the median infused volume of the vasopressin group was not small and despite its rarity, adverse effects of vasopressin can occur [15]. Shokeir et al reported that the use of an oxytocin drip during hysteroscopic endometrial resection could result in a smaller decrease of serum sodium level; nonetheless, the infused volume did not differ between the oxytocin drip and placebo groups (4180 mL vs. 4500 mL, respectively) [7]. In our study, the mean infused fluid of the MI group was only 1705 mL.…”

“…In an attempt to decrease the incidence of dilutional hyponatremia or the systemic absorption of the distending media, various methods have been used [4], including automated fluid monitoring [5,6], intraoperative oxytocin or vasopressin use [7,8], pretreatment with danazol or gonadotropin-releasing hormone agonists [9,10], use of 1.5% glycine [11], or use of a bipolar resectoscope [12]. In order to minimize the amount of distending media infused during hysteroscopic procedures, we used the manual syringe infusion (MI) method to infuse distending media.…”

BSGE/ESGE guideline on management of fluid distension media in operative hysteroscopy

“…In a randomized study [58] 48 women undergoing TCRE for abnormal uterine bleeding, were randomised to intravenous oxytocin infusion or saline infusion intraoperatively. There was a significant lower glycine deficit and decrease in serum sodium concentration in the oxytocin group, however the numbers in their study were quite small.…”