An Ulcerating Verrucous Plaque on the Foot

Ho, Julia; Diven, Dayna G.; Butler, Pamela J.; Tyring, Stephen K.

doi:10.1001/archderm.136.4.547-a

Cited by 27 publications

(21 citation statements)

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“…Verrucous carcinoma grows slowly and rarely metastasizes but displays locally aggressive features. It is found most commonly on the sole or ball of the foot also on knee, leg and web spaces of the toes [12, 13]. Foul-smelling keratogenous material may be excreted through multiple sinus openings.…”

Section: Discussionmentioning

confidence: 99%

Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report

Pempinello

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Pempinello

et al. 2013

Case Reports in Oncological Medicine

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Verrucous carcinoma of the foot often affects deep structures such as tendons, muscles, or bones. A 74-year-old man presented with a foot lesion that had been diagnosed as a skin infection 7 years earlier. He was treated with multiple excisions and superficial biopsies associated with antibiotic therapy without success. In our department he underwent an aggressive and accurate debridement with marginal excision harvesting multiple biopsies. Pathological evaluation of tissue at the time of operation confirmed the diagnosis of verrucous carcinoma of the foot. Therefore, the patient underwent an amputation below knee, and there were no postoperative complications; the patient was able to walk with the aid of a prosthesis with no signs of recurrence. The lesion follows a chronic course evolving from a discrete focal lesion to a large fungating deeply penetrating mass often compromised by local infection. The slow growth and confusing early-stage appearances can lead to delays in diagnosis of 8 to 15 years causing the extracutaneous involvement that requires a leg amputation. Many patients are initially treated with many topical medications without success, and most tumors have been treated as recalcitrant warts or corns for some time, whereas the basic approach is surgical.

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Section: Discussionmentioning

confidence: 99%

Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report

Pempinello

Бова

Pempinello

et al. 2013

Case Reports in Oncological Medicine

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“…Verrucous carcinoma more commonly affects males and is found most often in patients in their 50s 3. When feet are affected, the tumour occurs predominantly on the anterior weight‐bearing part of the sole of the foot and typically the history is one of a recalcitrant plantar wart or epidermal hyperplasia with recurrence after local excision 3…”

Section: Discussionmentioning

confidence: 99%

“…Diabetic patients with neuropathy and peripheral vascular disease have been reported to have altered wound healing and inflammatory responses to necrotic tissue and disturbed angiogenesis, and therefore will be more vulnerable to developing such a tumour 4. Some studies have shown that there may be a viral origin to verrucous carcinoma because of a close relationship with plantar warts 3, 5…”

Section: Discussionmentioning

confidence: 99%

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The remarkable case of verrucous carcinoma: a rare find

2013

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“…Through the years similar tumors have been described in other locations 2–4 . According to the anatomic localization, four types are now recognized: (1) VC of the oral cavity known as Ackerman's tumor or oral florid papillomatosis; 1 (2) VC of the anogenital area also known as giant condyloma of Buschke and Lowenstein or warty squamous cell carcinoma; 5,6 (3) VC of the soles also known as epithelioma cuniculatum (EC); 7–9 and (4) VC at other sites 2–4,10 …”

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confidence: 99%