An Unclear Anemia in an Elderly Subject with Aortic Stenosis

Magro, Valerio Massimo

doi:10.15197/sabad.1.12.35

Cited by 1 publication

(3 citation statements)

References 20 publications

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“…This resulted in three studies being eliminated, and ultimately 18 studies were included in this systematic review. Table 1 shown below is a summary of the pertinent findings of the 18 studies that were included in this systematic review [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. The aim of this prospective cohort was to ascertain the link between Von Willebrand factor levels and patients undergoing TAVI.…”

Section: Resultsmentioning

confidence: 99%

“…GIB: gastrointestinal bleeding; VWF: Von Willebrand factor; VWS: Von Willebrand factor syndrome; MGUS: monoclonal gammopathy of undetermined significance; NH-L: non-Hodgkin's lymphoma Angiodysplasia: Angiodysplasia refers to an acquired vascular aberration in which the blood vessels of the GI tract form pathological tortuous arteriovenous (AV) malformations in the mucosa and submucosa [1,2,9]. It is the second most common cause of developing a lower GI bleed in patients over the age of 60 years [10].…”

Section: Pathophysiologymentioning

confidence: 99%

“…For definitive management, patients need to undergo aortic valvular replacement [9,10,17,18,19] as it can lead to the normalization of high molecular weight VWF multimer levels [6,19]. Valvular replacement can be done either via surgical replacement or via TAVR [9]. TAVR has steadily become a widely accepted treatment option for aortic stenosis.…”

Section: Aortic Valvular Replacementmentioning

confidence: 99%

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Multimodal Treatment and Diagnostic Modalities in the Setting of Heyde’s Syndrome: A Systematic Review

Jamil¹,

Tran²,

Mansoor³

et al. 2022

Cureus

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Heyde's syndrome encompasses the triad of aortic stenosis (AS), angiodysplasia, and acquired Von Willebrand's disease (aVWD). The disease itself is a rare association that affects a small subset of patients who suffer from aortic stenosis. Nonetheless, it represents a vital area of clinical interest and is woefully underreported in the literature. Patients with Heyde's syndrome develop gastrointestinal bleeding (GI) as a result of angiodysplasia and due to lack of adequate hemostasis, they tend to be positively predisposed toward developing gastrointestinal hemorrhage. Due to the glaring lack of comprehensive literature on Heyde's syndrome, this systematic review aims to bridge the gap by elucidating the various diagnostic and treatment options available to clinicians for Heyde's syndrome patients as well as to give a detailed account of the pathophysiology of the disease. This systematic review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Google Scholar, Gulf Medical University (GMU) e-library, and PubMed were thoroughly searched for studies done in the last 10 years, which corresponds with our outlined inclusion and exclusion criteria. Relevant studies were then selected on the basis of their abstracts and titles. These studies then underwent a comprehensive quality assessment in which any papers which did not meet this study's eligibility criteria were omitted. Overall, 18 studies fulfilled the criteria of this systematic review.

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