An uncommon complication of a common disease: Varicella zoster myelitis

Mahapitiya, S; Wijeweera, K. P. I.; Hordagoda, Hemal; Bandara, Wdmsd

doi:10.4038/jpgim.8238

Cited by 1 publication

(3 citation statements)

References 10 publications

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“…Several cases of VZV myelitis in adult patients have been described in the literature [11,[14][15][16][17][18][19][20][21]. Some of these cases concerned immunocompetent patients aged 20 to 79 years [14][15][16][17][18][19]. In our case, our patient had no defect, the biological balance was normal (blood sugar, hepatic, HIV serology, CD4).…”

Section: Discussionmentioning

confidence: 66%

“…This study reports a case of acute transverse myelitis caused by VZV infection in an adult immunocompetent patient. Several cases of VZV myelitis in adult patients have been described in the literature [11,[14][15][16][17][18][19][20][21]. Some of these cases concerned immunocompetent patients aged 20 to 79 years [14][15][16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

“…Corticosteroid therapy was combined as a 120 mg/day bolus for 3 days followed by oral corticosteroid therapy. In some studies, patients were treated with only intravenous acyclovir for 21 days without steroids [17,19]. However, the use of acyclovir was not consistent in all series.…”

Section: Discussionmentioning

confidence: 99%

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Myelitis due to Varicella-Zoster Infection in an Adult Immunocompetent Patient at Yalgado Ouedraogo University Teaching Hospital (Burkina Faso)

Dabilgou¹,

Dao²,

Dravé³

et al. 2021

Int J Trop Dis

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Background: Varicella Zoster Virus (VZV) is a ubiquitous virus and is causing both diseases of varicella and herpes zoster. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. Case presentation:We reported a case of transverse myelitis caused by VZV in an immunocompetent young patient. A 42-year-old man was presented to the Neurology department in June 2019 with the complaints of cutaneous rash, lower limbs weakness and anal and urinary incontinence. The neurological manifestations occurred at twelve days after cutaneous rash. Spine MRI showed extensive intramedullary T2 hypersignal of C6 to C7. White blood cell showed hyperleucocytosis. Cerebrospinal fluid (CSF) showed leukocytosis (40 cells/µL) with increased levels of protein (1.134 g/l). CSF culture for bacteria and fungi were negative. The patient was treated with oral acyclovir, corticotherapy and functional rehabilitation. Complete recovery occurred after 4 weeks of treatment.Conclusions: Transverse VZV myelitis in an adult immunocompetent patient following cutaneous rash is extremely rare in our context. Clinical outcome was favorable after recommended dose of acyclovir, corticotherapy and rehabilitation.

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