An unusual complication of systemic lupus erythematosus: bacterial meningitis caused by <i>Streptococcus agalactiae</i>

Kim, B. S.; Kim, S. H.; Kim, S. J.; Jang, Bong-Seok; Kim, M. B.; Oh, Chang‐Keun; Kwon, Yoo Wook; Kwon, Kyung‐Sool

doi:10.1111/j.1468-3083.2007.02167.x

Cited by 7 publications

(2 citation statements)

References 4 publications

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“…Only one case was identified out of 101 major infections, with the causative agent being Streptococcus pneumoniae 22 . Only three other cases of GBS meningitis in patients with SLE have been reported 3 , 23 .…”

Section: Discussionmentioning

confidence: 99%

Case Report: Group B Streptococcus meningitis in an adolescent

et al. 2014

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Streptococcus agalactiae (group B Streptococcus, GBS) usually colonizes the gastrointestinal and lower genital tracts of asymptomatic hosts, yet the incidence of invasive disease is on the rise . We describe a case of an 18 year old woman, recently diagnosed with lupus, who reported a spontaneous abortion six weeks prior to her hospitalization. She presented with fever, altered mental status, and meningeal signs, paired with a positive blood culture for GBS. Magnetic resonance imaging of her brain demonstrated an extra-axial fluid collection, and she was diagnosed with meningitis. She received prolonged intravenous antibiotic therapy and aggressive treatment for lupus, leading to clinical recovery. This case illustrates the importance of recognizing GBS as a potential pathogen in all patients presenting with CNS infection .

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Section: Discussionmentioning

confidence: 99%

Case Report: Group B Streptococcus meningitis in an adolescent

et al. 2014

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“…Additionally, several recent reports suggest that the incidence of GBS disease has also been increasing among older adults with underlying medical conditions affecting their immune system [3]. There is only one published report retrievable by a Medline search (using SLE and GBS) documenting a serious GBS infection involving an 18-year-old adolescent with SLE [4]. …”

Section: Introductionmentioning

confidence: 99%

Invasive Group B Streptococcal Disease in Two Pediatric Patients with Systemic Lupus Erythematosus

Bromberg

Jodorkovsky

2013

Case Reports in Pediatrics

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Systemic lupus erythematosus (SLE) is an autoimmune disease associated with high morbidity and mortality, often caused by infection. We report two patients with SLE who were treated with steroids and immunosuppressive medication and then developed invasive Group B Streptococcus (GBS) infections. While GBS infection is rare in the nonneonatal pediatric age group, GBS should be considered when treating SLE patients presenting with signs of infection.

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The lichenoid reaction pattern (‘interface dermatitis’)

Weedon

2010

Weedon's Skin Pathology

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An unusual complication of systemic lupus erythematosus: bacterial meningitis caused by Streptococcus agalactiae

Cited by 7 publications

References 4 publications

Case Report: Group B Streptococcus meningitis in an adolescent

Case Report: Group B Streptococcus meningitis in an adolescent

Invasive Group B Streptococcal Disease in Two Pediatric Patients with Systemic Lupus Erythematosus

The lichenoid reaction pattern (‘interface dermatitis’)

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