An unusual extranodal T-cell non-Hodgkin lymphoma

Coats, Josh T.; Mackie, Anna; Kernohan, Neil M.; Ramkumar, Prasad Guntur; McMahon, Lesley; Goodlad, John; Tauro, Sudhir

doi:10.1016/s0140-6736(16)30447-0

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…Aetiologies in the literature reported to mimic PTCL include Hodgkin’s disease,10 cirrhosis and other hepatic diseases,11–13 cellulitis,14 stroke,15 ulcer,16 post-transplant lymphoproliferative disease (PTLD)17 and FUO18 (table 1). In addition, there are reports of PTCL having been diagnosed after initially mimicking alternate diagnoses, including Mycobacterium,19 EBV,20–22 natural killer lymphoma,23 tuberculosis24 and syphilis25 (table 2).…”

Section: Discussionmentioning

confidence: 99%

Peripheral T-cell lymphoma mimicking classic Hodgkin’s lymphoma in a patient presenting with fevers of unknown origin

Butler¹,

Skelton

Patel

et al. 2018

BMJ Case Reports

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A 52-year-old man presented to our hospital for further workup of fever of unknown origin after an extensive workup at an outside hospital had failed to reveal a diagnosis. At the outside hospital, he underwent excisional biopsy of the left supraclavicular lymph node, which showed non-necrotising granulomatous changes, and a bone marrow biopsy which showed a normocellular marrow. He was discharged without a diagnosis with recommendations to present to a tertiary hospital. During his admission, his hospital course was complicated by new direct hyperbilirubinaemia and eosinophilia, prompting liver and skin biopsies which showed CD30+ and CD3+ cells. He subsequently underwent left axillary lymph node biopsy, which was reported as 'classic Hodgkin's lymphoma'. With worsening lab values and T cells noted on liver and skin biopsies, excisional lymph node biopsy was sent to the National Institute of Health, where it was confirmed patient had peripheral T cell lymphoma.

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