“…Approximately 80% of parathyroid adenomas present with asymptomatic hypercalcemia while giant adenomas mostly demonstrate severe symptoms due to the metabolic abnormalities. Fatigue, muscular, skeletal, and cardiac complaints are major symptoms that are seen in most of the patients with giant adenomas because of severe hypercalcemia (8)(9)(10). Previously reported asymptomatic PHP cases of giant parathyroid adenomas showed a weight under 31 g (11,12).…”