An Unusual Mesenteric Tumor ‘Paraganglioma’: A Case Report

Özkan, Zeynep; Özdemir, Cengizhan Şan; Yaşar, Günay; Altas, Onder; Koç, Mustafa; Gül, Yeliz; Durdağ, Emre

doi:10.5812/ircmj.16837

Cited by 6 publications

(11 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Given the capacity of a paraganglioma to secrete catecholamines, plasma or urinary metanephrines have been described in the literature as a very sensitive technique. Unfortunately, the secreting property is only found in 25% of mesenteric paragangliomas [1]. Anatomical imagery with US/CT/MRI are equally as effective in identifying these abdominal masses.…”

Section: Discussionmentioning

confidence: 99%

“…Paraganglioma are rare type of neuroendocrine tumor that arise from embryonal neural crest [1]. Paraganglia contain tissues such as the adrenal medulla, carotid and aortic bodies, paraganglia in sympathetic and parasympathetic nerves and organs of Zuckerkandl.…”

Section: Introductionmentioning

confidence: 99%

“…With an annual incidence estimated at 1/100,000, paragangliomas represent ten percent of catecholamine secreting tumors. Paragangliomas arise from chromaffin tissue most commonly found in the Zuckerkandl body, the Manuscript received: 5 th January 2020 Reviewed: 15 th January 2020 Author Corrected: 25 th January 2020 Accepted for Publication: 28 th January 2020 sympathetic plexus of the urinary bladder, the kidneys, and the heart or in the sympathetic ganglia of the head or neck [1]. Some paragangliomas have been described in the Gastrointestinal System, the majority of which were associated with the duodenum.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A rare mesentric tumor “paraganglioma” – a case report

Gidwani

Jain

Agarwal

2020

Trop J Pathol Microbiol

View full text Add to dashboard Cite

Paraganglioma are rare type of neuroendocrine tumors that arise from embryonal neural crest. Paraganglioma of adrenal medulla is known as Pheochromocytoma. Extra adrenal localization has incidence of 2-8 per million people per year, which can extend from upper cervical region to pelvis related to autonomic nervous system. Even rarer is occurrence of paragangliomas outside the usual distribution of paraganglionic tissue. Mesenteric paragangliomas are extremely rare. The present case was of a nonfunctional extra adrenal paraganglioma occurring in a 43-year-old male presented with complain of pain in abdomen and mild discomfort. Abdominal CECT revealed well defined enhancing solid mass with central necrosis in right side of mesentry. Explorative laparotomy and surgical excision were done, on histology typical "zellballen" pattern was found. Paragangliomas are rare neuroendocrine tumor known to store and secrete catecholamines and hence are known as functional paragangliomas and may present with symptoms like headache, sweating, palpitations and hypertension. On other hand, they may remain silent and non-functional and present with vague symptoms like pain abdomen due to episodic release of catecholamines. Surgical excision is treatment of choice. Long term follow up is mandatory as tumor is prone to recur and metastasize.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A rare mesentric tumor “paraganglioma” – a case report

Gidwani

Jain

Agarwal

2020

Trop J Pathol Microbiol

View full text Add to dashboard Cite

show abstract

“…Primary tumors arising in the mesentery have been reported as rare tumors; however, small primary tumors are being identified more easily as diagnostic imaging systems have improved. These tumors are typically mesenchymal: Paraganglioma ( 1 , 2 ), lipoma ( 3 ), Schwannoma ( 4 , 5 ), leiomyosarcoma ( 6 ), liposarcoma ( 7 ), osteosarcoma ( 8 ), gastrointestinal stromal tumors (GIST) ( 9 ), solitary fibrous tumors (SFT) ( 10 ), hemangioma ( 11 ), lymphangioma ( 12 ), smooth muscle tumors ( 10 ) and several types of cystic tumors ( 13 ). The majority of patients with primary tumors arising in the mesentery present with abdominal pain, and ultrasonography and/or abdominal computed tomography (CT) and/or magnetic resonance imaging (MRI) are performed.…”

Section: Introductionmentioning

confidence: 99%

A mesenteric solid tumor with unusual features in a young male: A case report

Ichikawa

Maeda

Mizojiri

et al. 2017

Molecular and Clinical Oncology

View full text Add to dashboard Cite

The current study presents a mesenteric mesenchymal tumor case, with unusual features in diagnostic imaging and histology. A 16-year-old male was admitted to the hospital with abdominal pain. Computed tomography (CT) revealed an abdominal mass, 2 cm in diameter. The results of contrast-enhanced CT, magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography indicated no specific features suggestive of its histology. Two arteries branching from the superior mesenteric artery were observed feeding the hypervascular tumor. After endoscopic and other laboratory findings revealed no additional lesions, the lesion was diagnosed as a primary mesenteric tumor. As the possibility of malignancy and future bleeding from this tumor could not be ruled out, a resection of the tumor was performed. During the surgery, the tumor, which was well circumscribed and hypervascular, was located in the mesentery of the jejunum. The resected tumor did not exhibit typical histological characteristics, and was labeled as ‘myxoid smooth muscle neoplasm of uncertain biologic potential’. At 2 years after surgery, the patient remained well without evidence of recurrence. As primary mesenteric tumors are rare, particularly in young patients, it is considered important that this type of unusual tumor be included in the differential diagnosis for mesenteric tumors.

show abstract

“…Tumor occuring within the adrenal medulla are called pheochromocytoma, and those developing in extra-adrenal locations (5-10% of cases) are referred to as paraganglioma (1,2). Paraganglioma secrete catecholamines and cause malignant hypertension or symptoms such as headaches, palpitations, and diaphoresis.…”

Section: Introductionmentioning

confidence: 99%