An Unusual N-Alkylation Reaction During the Oxidative Addition of Hexafluoroacetone and Tetrachloro-o-benzoquinone to P-Bis(2-chloroethyl)amino-Substituted λ3P-Compounds

Synthesis of moxifloxacin–Au (III) and Ag (I) metal complexes and their biological activities

“…The magnetic moments of the present moxifloxacin of Au (III) and Ag (I) complexes are 1.80 and 1.75 BM, respectively. The magnetic moments of these ranges are suggested octahedral geometry for Au (III) and tetrahedral geometry for Ag (I) complex (Kadyrov et al 1996;Neda et al 1996;Sonnenburg et al 1994).…”

5-Ethyl-6-oxo-4-thioxo-1,3,2-oxazaphospholidino[3,2-a][1,3,2]benzodiazaphosphorine

“…In new pharmaceuticals and agrochemicals, the incorporation of heterocycles is recommended to improve the biological activity. In particular, phospha-heterocycles, such as benzoannulated and related analogs of cyclophosphamide, have shown antitumor activity, and have received considerable interest in the ®elds of chemistry, medicine and agricultural science (Rao et al, 2000;Neda et al, 1996;Viljanen et al, 1998;Huang & Chen, 2000).…”

Efficient synthesis and crystal structure of 2‐propyl‐5‐(substituted)phenyl‐1,4‐dioxo‐1,2,3,4,5,6,7,8‐octahydro‐[1,4,2]diazaphosphorino[1,2‐a] [1,3,2]benzodiazaphosphorine 3‐oxides

“…A sizeable number of endogenous compounds that play a key role in regulation of various life processes consist of fused heterocycles. Furthermore, benzoannulated and related analogs of cyclophosphamide possess antitumor activity and have also created an increasingly wide interest in chemistry, medicine, and agricultural science [17][18][19][20]. As a part of our ongoing program to develop novel antitumor and antiviral agents with high activity and low toxicity, some 2-propyl-5-(substituted)phenyl-1, 4-dioxo-1,2,3,4,5,6,7,8-octahydro- [1,4,2]diazaphosphorino [1,2-a][1,3,2]benzodiazaphosphorine 3-oxides have been designed incorporating the proximate carbonyl and phosphoryl groups into the benzoannulated phosphadiamide heterocycle, and they have been synthesized in acceptable yields.…”