An update of interbody cages for spine fusion surgeries: from shape design to materials

Li, Guangshen; Yang, Lei; Wu, Gang; Qian, Zhiguo; Li, Haijun

doi:10.1080/17434440.2022.2165912

Expert Review of Medical Devices

2022

DOI: 10.1080/17434440.2022.2165912

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An update of interbody cages for spine fusion surgeries: from shape design to materials

Guangshen Li

Lei Yang

Gang Wu

et al.

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Cited by 3 publications

(2 citation statements)

References 120 publications

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“…2 Stemming from traditional grafting with plating systems, several implants have been developed to decrease implant footprint, thereby decreasing the rates of postoperative soft tissue complications and dysphagia. 3 Among these are stand-alone implants, which are designed to simultaneously serve as an interbody spacer while providing rigid fixation for the construct with minimal impingement upon prevertebral soft tissue. 4 Iunes et al 5 and Bucci et al 6 found that zero-profile (ZP) cervical implants were associated with a lower rate of pseudarthrosis relative to grafts with plating, whereas Njoku et al 7 found equivalent outcomes.…”

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confidence: 99%

“…In the United States alone, over 132,000 ACDF surgeries are done annually for patients failing nonsurgical treatments 2 . Stemming from traditional grafting with plating systems, several implants have been developed to decrease implant footprint, thereby decreasing the rates of postoperative soft tissue complications and dysphagia 3 . Among these are stand-alone implants, which are designed to simultaneously serve as an interbody spacer while providing rigid fixation for the construct with minimal impingement upon prevertebral soft tissue 4 …”

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confidence: 99%

See 1 more Smart Citation

No Difference in Surgical Outcomes Between Stand-Alone Devices and Anterior Plating for 1-2 Level Anterior Cervical Discectomy and Fusion

Tao,

Matur,

Street

et al. 2023

Spine

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Study Design: Retrospective cohort. Objective: Compare rates of all-cause surgical and medical complications between zero-profile (stand-alone) implants versus any graft type with anterior plate in patients undergoing 1-2 level anterior cervical discectomy and fusion (ACDF) for treatment of degenerative cervical myeloradiculopathy. Summary of Background Data: Degenerative cervical myeloradiculopathy is increasingly prevalent in older adults. ACDF is a common surgical procedure for decompression of neural structures and stabilization and has been shown to have excellent outcomes. While ACDFs performed with a graft and plate has been the gold standard, more recently, zero-profile implants were developed to decrease implant related complications, such as severe postoperative dysphagia. However, there is a paucity of papers comparing the surgical and medical complications profile of zero-profile (stand-alone) implants to grafts with plating systems. Methods: Data was extracted from the PearlDiver Mariner Database using CPT codes to classify patients into 1-level, 2-levels, and total 1-2 level ACDFs. Patients undergoing surgery for non-degenerative pathologies such as tumors, trauma, or infection were excluded. Results: 1:1 exact matching created two equal groups of 7,284 patients that underwent 1-2 level ACDF with either grafting with a plate or zero-profile (standalone) implant. There were no statistically significant difference in all-cause surgical complications, pseudarthrosis rate, dysphagia or need for revision surgery between both cohorts (RR 0.99, 95% CI 0.80-1.21, P = 0.95). Additionally, all-cause medical complications were similar between both cohorts (RR 1.07, 95% CI 0.862-1.330, P = 0.573) or any specific surgical or medical complication included in this study. Conclusion: After 1:1 exact matching, the results of this study suggest that zero-profile (stand-alone) implants have similar outcomes compared to grafts with plating systems, with no observed differences in all-cause surgical or medical complications profile.

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mentioning

confidence: 99%

mentioning

confidence: 99%

No Difference in Surgical Outcomes Between Stand-Alone Devices and Anterior Plating for 1-2 Level Anterior Cervical Discectomy and Fusion

Tao,

Matur,

Street

et al. 2023

Spine

View full text Add to dashboard Cite

show abstract

Enhanced osteogenesis and inflammation suppression in 3D printed n-HA/PA66 composite scaffolds with PTH(1-34)-loaded nPDA coatings

Zeng,

Wang,

et al. 2024

Composites Part B: Engineering

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Research progress of metal-based additive manufacturing in medical implants

Zhai,

Zhang,

Wang

et al. 2023

Reviews on Advanced Materials Science

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Metal-based additive manufacturing has gained significant attention in the field of medical implants over the past decade. The application of 3D-printing technology in medical implants offers several advantages over traditional manufacturing methods, including increased design flexibility for implant customization, reduced lead time for emergency cases, and the ability to create complex geometry shapes for patient-specific implants. In this review study, the working principles and conditions of metal 3D-printing technologies such as selective laser sintering, selective laser melting, and electron beam melting, as well as their applications and advantages in the medical field, are investigated in detail. The application scenarios and research status of non-degradable metals including titanium alloy, medical stainless steel, etc., and degradable metals like magnesium alloy are introduced as printing materials. We discuss the improvement of mechanical properties and biocompatibility of implants through surface modification, porous structure design, and the optimization of molding processes. Finally, the biocompatibility issues and challenges caused by the accuracy of CT imaging, fabrication, implant placement, and other aspects are summarized.

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An update of interbody cages for spine fusion surgeries: from shape design to materials

Cited by 3 publications

References 120 publications

No Difference in Surgical Outcomes Between Stand-Alone Devices and Anterior Plating for 1-2 Level Anterior Cervical Discectomy and Fusion

No Difference in Surgical Outcomes Between Stand-Alone Devices and Anterior Plating for 1-2 Level Anterior Cervical Discectomy and Fusion

Enhanced osteogenesis and inflammation suppression in 3D printed n-HA/PA66 composite scaffolds with PTH(1-34)-loaded nPDA coatings

Research progress of metal-based additive manufacturing in medical implants

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