An update on adenomyosis

Lévy, G.; Dehaene, A.; Nicolas, Laurent; Lernout, M.; Collinet, Pierre; Lucot, J P; Lions, Christophe; Poncelet, E.

doi:10.1016/j.diii.2012.10.012

Cited by 102 publications

(101 citation statements)

References 39 publications

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“…This may be because 65% of our patients were less than 35 years of age and the prevalence of adenomyosis is lower at that age [11]. However, the low prevalence rate may also indicate that our diagnostic sensitivity for adenomyosis might be lower, and some patients with mild adenomyosis might have been included in our control group, weakening the differences between groups 1 and 2.…”

Section: Discussionmentioning

confidence: 74%

Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study

Yan

Ding

Tang

et al. 2013

Gynecol Obstet Invest

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Aims: To study the effect of adenomyosis on in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes in infertile patients. Methods: We performed a retrospective, database-searched cohort study based on 10,268 patients undergoing controlled ovarian hyperstimulation and IVF/ICSI between 2009 and 2011 in our unit. Adenomyosis was diagnosed by transvaginal ultrasound. A high-quality matched cohort study with strict inclusion criteria was conducted. We compared the basic characteristics and main IVF/ICSI outcomes between the two groups. Results: We identified 83 patients with adenomyosis, of whom we included 77, and strictly matched them to 77 patients without adenomyosis. Higher day 3 estrogen levels and a longer duration of gonadotropin stimulation days were found in women with adenomyosis compared to control subjects. Patients with adenomyosis had a nonsignificant trend toward a lower clinical pregnancy rate and a higher miscarriage rate (p = 0.103 and 0.09, respectively). The delivery rate was significantly lower in the adenomyosis group in comparison to the matched controls (p = 0.022). Conclusions: Within the limitations of a retrospective study (albeit with a remarkably large number of observations), our results suggest that transvaginal ultrasound-diagnosed adenomyosis could have a negative impact on the main IVF/ICSI outcomes. Improving the diagnostic validity and scoring of disease severity in patients with adenomyosis is suggested.

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Section: Discussionmentioning

confidence: 74%

Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study

Yan

Ding

Tang

et al. 2013

Gynecol Obstet Invest

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“…31 It was thought that this represented myometrial smooth muscle hyperplasia and hypertrophy reaction due to presence of ectopic endometrial glands within the myometrium. 19,29 In the index study myometrial cysts had lowest sensitivity (6.52%) and highest specificity. Thus from the index study it was concluded that the absence of the myometrial cysts does not rule out the disease but its presence is highly suggestive of adenomyosis.…”

Section: Ultrasonographymentioning

confidence: 99%

Clinical and ultrasonological features of adenomyosis and its histopathological correlation

Gupta

Goel

Agrawal

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…It is a common disease, affecting approximately 20-30 % of adult women [35]. More importantly, though, two-thirds of these women present with menometrorrhagia, dysmenorrhea, dyspareunia, pelvic pain, and possibly infertility [36].…”

Section: Mr-guided High-intensity Focused Ultrasound For Uterine Adenmentioning

confidence: 99%

Genitourinary Applications of MR-Guided High-Intensity Focused Ultrasound

2014

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An update on adenomyosis

Cited by 102 publications

References 39 publications

Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study

Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study

Clinical and ultrasonological features of adenomyosis and its histopathological correlation

Genitourinary Applications of MR-Guided High-Intensity Focused Ultrasound

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