An Update on Facial Skin Rejuvenation Effectiveness of Mesotherapy EBM V

Abstract

Although it appears to be a simple, easy, and financially attractive therapeutic modality, skin rejuvenation mesotherapy is a controversial cosmetic procedure and proof of its efficacy is still lacking. The authors have published a review about this therapeutic modality more than a decade ago. Few clinical studies evaluating its efficacy and safety were available then without any conclusive scientific evidence about its efficacy; nevertheless, mesotherapy has continued to be performed at a relatively high financial cost to patients by many nonmedical and medical professionals for antiaging purposes. The authors have published a review about this therapeutic modality more than a decade ago. The current review is an update aimed at identifying any evidence about the scientific validity and efficacy of this approach that has emerged since then. No clinical valuable new data and new information has been identified. As by American Society of Plastic Surgeons (ASPS) policy statement updated and approved in 2019, mesotherapy for skin rejuvenation is currently not Food and Drug Administration approved. Until more conclusive data is available, skin rejuvenation mesotherapy cannot be recommended for routine skin rejuvenation clinical application.

Alopecia After Cosmetic Injection Procedures: A Review

“…According to the American society of Plastic Surgeons policy statement in 2019, no medication has been approved for mesotherapy for the purposes of skin rejuvenation by the FDA. 1,2 Furthermore, data supporting the efficacy of such procedures in treating different types of alopecias are scarce. 3 Mesotherapy with dutasteride has become widely popular, despite lack of controlled clinical trials.…”

Puzzle Facelift: A Nonsurgical, Whole Treatment for Facial Modeling and Rejuvenation

“…All rights reserved. specific types of hyaluronic acid (HA) filling, whereas skin texture defects may be addressed by less cohesive hyaluronic acid (HA), botulinum toxin and other treatments such as mesotherapy and energy-based devices [10][11][12][13][14] .…”

“…Moreover, bone structure deficiency and lack of volume may be addressed with specific types of hyaluronic acid (HA) filling, whereas skin texture defects may be addressed by less cohesive HA, botulinum toxin, and other treatments such as mesotherapy and energy-based devices. [10][11][12][13][14] In this paper, we would like to propose a whole facial treatment algorithm that we will call "nonsurgical puzzle facelift," which considers a series of evidence reporting the methodology used to achieve an optimal aesthetic result with different G prime crosslinked HA, thereby using a nonsurgical procedure for facial rejuvenation and modeling. [15][16][17][18][19] The objective of this paper is to discuss an overview of the approaches recently used to reach the "face beauty" concept in practice.…”

“…Moreover, bone structure deficiency and lack of volume may be addressed with specific types of hyaluronic acid (HA) filling, whereas skin texture defects may be addressed by less cohesive HA, botulinum toxin, and other treatments such as mesotherapy and energy-based devices. 10 11 12 13 14…”