2005
DOI: 10.1007/s11940-005-0022-2
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An update on myasthenic crisis

Abstract: Myasthenia gravis (MG) is the most common disorder of the neuromuscular junction. Myasthenia crisis, defined as respiratory failure requiring mechanical ventilation in MG, is a common life-threatening complication that occurs in approximately 15% to 20% of patients with MG during their life time. The advent of effective mechanical ventilation, specialized neurointensive care units and the widespread use of immunotherapies have substantially altered the prognosis of myasthenic crisis. Early intubation and mecha… Show more

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Cited by 34 publications
(87 citation statements)
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“…In most patients, repeated measurements of VC and PImax help determine the need for and timing of elective intubation (Ahmed et al, 2005;. These indices can be measured as often as every two hours, but typically every four hours.…”
Section: Indications and Predictors For Endotracheal Intubationmentioning
confidence: 99%
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“…In most patients, repeated measurements of VC and PImax help determine the need for and timing of elective intubation (Ahmed et al, 2005;. These indices can be measured as often as every two hours, but typically every four hours.…”
Section: Indications and Predictors For Endotracheal Intubationmentioning
confidence: 99%
“…Thus, these respiratory parameters should always be interpreted in the context of the clinical symptoms and signs, as well as the trend in these measures. Regardless of respiratory function indices, the need for mechanical ventilation is a sufficient criterion to define myasthenic crisis (Ahmed et al, 2005). With close monitoring of the patient's condition, endotracheal intubation can often be performed electively rather than as an emergent response to precipitous respiratory collapse (Juel, 2004;Bird and Teener, 2001).…”
Section: Indications and Predictors For Endotracheal Intubationmentioning
confidence: 99%
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