An Updated Review on Traditional and Modern Aspects of Vitex negundo

Abstract

Vitex negundo is a traditional herb known for its medicinal properties in Unani, Ayurveda, Siddha, Chinese, Roman, and other traditional systems of medicine. Traditionally, it is used as anthelminthic, antitoxin, aphrodisiac, contraceptive, antimalarial, analgesic, antiinflamatory, antiasthmatic, vermifuge, etc. All parts of V. negundo contain number of phytoconstituents like alkaloids, fatty acids, flavonoids, glycosidic irridoids, lignans, phenols, steroids, tannins and di- and sesquiterpenes. Due to the presence of a variety of secondary metabolites, V. negundo is used in different types of diseases or disorders by traditional pracctitioners for the treatment of spermatorrhoea, stomachache, asthma, cold, diarrhoea, indigestion, gallstone, hernia, eye disorders, rheumatism, irritable bladder and dysmenorrhea, headache, migraine, kwashiorkor, neck gland sores, tubercular neck swelling, reddened, arthritis, jaundice, urticaria, eczema and liver disorders. It is most widely used for curing disorders of the reproductive system like vital power, depression, frail erection without libido, self-contempt for sexual abuse, stool containing prostatic fluid, and testicle pain. Facts were gathered from databases such as PubMed, Google Scholar, Springer, Scopus, and ScienceDirect, as well as literature found in books of medicinal plants. It has recently been reported to have cytotoxic properties against various types of cancer cells. It works by inducing apoptosis via the mitochondrial and TRIAL pathways and stopping the cell cycle. This review sheds light upon the ethnomedicinal uses, phytochemistry, different extraction procedures, and pharmacology of V. negundo. In conclusion, it was found that this traditional herb had an emerging past, exciting present and promising future for the treatment of several diseases.

Formulation and Evaluation of Multipurpose Herbal Cream

“…Extraction was carried out by Maceration method. The supernatant after 4-5 days was filtered out [7] . 1.5) Collection of Turmeric (Curcuma long) Rhizomes Turmeric rhizomes are collected from herbal garden of Akluj.…”

“…It also exhibits antimicrobial, anti-tumor, insecticidal, hypoglycemic, anti-arthritic. In modern practices, the application of flowers of V. Negundo cures fever, diarrhoea, and hepatic problems and the fruits are given in headaches [7] .…”

Importance of conserving Vitex peduncularis: A depleting forest resource with immense ethnopharmacological uses

“…Vitex have been linked to a variety of energy attributes; in certain instances, these properties were described with the development of Traditional Chinese Medicine [11]. Different plant parts of V. negundo L [70,71,72,73,74] . V. trifolia L [75,76,77,78,79] .…”