“…Consequently, we propose that the availability and access to real-time health data through digital health technologies (DHTs) in Africa could facilitate (1) the application of rapid predictive monitoring systems, geographic information, and dashboards for disease surveillance, data visualization, and health decision-making; for example, vaccine and masks mandates, lockdowns, and quarantine measures; (2) good governance or policy decision-making and an inclusive regulatory or legal framework to deter excess bureaucracy and minimize the depletion of scarce resources; (3) leveraging of mHealth and social media analytics to obtain data that assess public sentiments, opinions, or information gaps and enable the creation and dissemination of tailored messages that address mis-or disinformation, vaccine hesitancy, and vaccine inequity; (4) comprehensive educational or training programs that expand digital literacy, health information-seeking behaviors, and precision health education or promotion. Overall, in this pandemic era, the fast-tracking adoption of digital technologies to collect, share, and analyze socio-behavioral and health data could further transform disease preparedness and response, mitigate the spread of infections, and optimize health care delivery services; for example, vaccine delivery, contact tracing, case containment, and management [11][12][13].…”