An X-linked agammaglobulinemia (XLA) patient with fever and disturbance of consciousness: infection with Torque teno virus?

Liu, Hui; Zhao, Jiajia; Yang, Chuwei; Liu, Yuanyuan

doi:10.1016/j.ijid.2021.11.041

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…TTV load is also significantly increased in patients with autoimmune inflammatory diseases [ 124 ]. People infected with TTV can probably get autoimmune diseases or have their severity affected due to the effect of this virus on the host’s immune system and its modulation [ 125 , 126 ]. Also, the increase in TTV DNA load in people with systemic lupus erythematosus, which is an autoimmune disease, is significant compared to healthy people.…”

Section: Immune System Diseasesmentioning

confidence: 99%

The mysterious anelloviruses: investigating its role in human diseases

Sabbaghian,

Gheitasi,

Shekarchi

et al. 2024

BMC Microbiol

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Anelloviruses (AVs) that infect the human population are members of the Anelloviridae family. They are widely distributed in human populations worldwide. Torque teno virus (TTV) was the first virus of this family to be identified and is estimated to be found in the serum of 80–90% of the human population. Sometime after the identification of TTV, Torque teno mini virus (TTMV) and Torque teno midi virus (TTMDV) were also identified and classified in this family. Since identifying these viruses, have been detected in various types of biological fluids of the human body, including blood and urine, as well as vital organs such as the liver and kidney. They can be transmitted from person to person through blood transfusions, fecal-oral contact, and possibly sexual intercourse. Recent studies on these newly introduced viruses show that although they are not directly related to human disease, they may be indirectly involved in initiating or exacerbating some human population-related diseases and viral infections. Among these diseases, we can mention various types of cancers, immune system diseases, viral infections, hepatitis, and AIDS. Also, they likely use the microRNAs (miRNAs) they encode to fulfill this cooperative role. Also, in recent years, the role of proliferation and their viral load, especially TTV, has been highlighted to indicate the immune system status of immunocompromised people or people who undergo organ transplants. Here, we review the possible role of these viruses in diseases that target humans and highlight them as important viruses that require further study. This review can provide new insights to researchers.

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Section: Immune System Diseasesmentioning

confidence: 99%

The mysterious anelloviruses: investigating its role in human diseases

Sabbaghian,

Gheitasi,

Shekarchi

et al. 2024

BMC Microbiol

View full text Add to dashboard Cite

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Torque Teno Virus and Cancers: Current Knowledge

et al. 2023

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Aim: The aim of this systematic review is to assess the current knowledge about the relationship between Torque teno virus (TTV) and cancer in different settings. Methods: A systematic search was conducted in Medline via PubMed, Embase and Cochrane Library from the inception to the end of January 2023. Results: 34 articles were included in the qualitative synthesis of this review and 2145 patients with solid tumors have been analyzed. The most prevalent cancer types were hepatocellular carcinoma (HCC) and lung cancer. Conclusion: TTV has proven its role as a marker of functional immune competence in the setting of hematopoietic stem cell transplantation (HSCT), but in the oncological field is yet to be defined.

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An X-linked agammaglobulinemia (XLA) patient with fever and disturbance of consciousness: infection with Torque teno virus?

Cited by 2 publications

References 11 publications

The mysterious anelloviruses: investigating its role in human diseases

The mysterious anelloviruses: investigating its role in human diseases

Torque Teno Virus and Cancers: Current Knowledge

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