Anaerobic bacteria isolated from decubitus ulcers

Peromet, M; Yourassowsky, E; Schoutens, E

doi:10.1007/bf01639650

Cited by 16 publications

(9 citation statements)

References 7 publications

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“…Moisture provided by this soilage accelerates sore formation, while fecal contamination predisposes to polymicrobial infection, including infection with Bacteroides species and other obligate anaerobes 8–11 . Such infections are associated with a putrid odor and occasionally with life‐threatening sepsis 9–11 . In fact, one patient in our institution died following anaerobic sepsis with Peptococcus and Eubacterium associated with a foul‐smelling sacral pressure sore.…”

Section: Discussionmentioning

confidence: 91%

“…Pressure sores arise most frequently in areas close to urinary and fecal soilage, i.e., over the hips, buttocks and sacrum 3,4 . Moisture provided by this soilage accelerates sore formation, while fecal contamination predisposes to polymicrobial infection, including infection with Bacteroides species and other obligate anaerobes 8–11 . Such infections are associated with a putrid odor and occasionally with life‐threatening sepsis 9–11 .…”

Section: Discussionmentioning

confidence: 99%

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Topical Metronidazole Therapy for Pressure Sores of Geriatric Patients

Gomolin

Brandt

1983

J American Geriatrics Society

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Topical Metronidazole Therapy for Pressure Sores of Geriatric Patients

Gomolin

Brandt

1983

J American Geriatrics Society

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“…Prior studies evaluating the microbiology of pressure ulcers in the general population have identified S. aureus, S. epidermidis, P. mirabilis, and P. aeruginosa as common bacterial species identified from ulcers. [36][37][38] In an extensive clinical compilation of 2500 cases of chronic pressure ulcers in patients with SCI, El-Toraei et al Table 3 Wound characteristics among studies examining pressure ulcers in individuals with SCI from the 11 studies included in our review…”

Section: Discussionmentioning

confidence: 99%

Bacteriology of pressure ulcers in individuals with spinal cord injury: What we know and what we should know

Dana

Bauman

2014

The Journal of Spinal Cord Medicine

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Individuals with spinal cord injury (SCI) are at increased risk for the development of pressure ulcers. These chronic wounds are debilitating and contribute to prolonged hospitalization and worse medical outcome. However, the species of bacteria and the role that specific species may play in delaying the healing of chronic pressure ulcers in the SCI population has not been well characterized. This study will review the literature regarding what is known currently about the bacteriology of pressure ulcers in individuals with SCI. An electronic literature search of MEDLINE (1966 to February 2014) was performed. Eleven studies detailing bacterial cultures of pressure ulcers in the SCI population met inclusion criteria and were selected for review. Among these studies, bacterial cultures were often polymicrobial with both aerobic and anaerobic bacteria identified with culture techniques that varied significantly. The most common organisms identified in pressure ulcers were Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, and Enterococcus faecalis. In general, wounds were poorly characterized with minimal to no physical description and/or location provided. Our present understanding of factors that may alter the microbiome of pressure ulcers in individuals with SCI is quite rudimentary, at best. Well-designed studies are needed to assess appropriate wound culture technique, the impact of bacterial composition on wound healing, development of infection, and the optimum medical and surgical approaches to wound care.

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“…In fact, only metronidazole (9,10) and clindamycin (9) have been shown to possess bactericidal activity in vitro against B. fragilis. Unfortunately, these two drugs do not act against aerobic gram-negative bacilli, frequently recovered in addition to Bacteroides strains in septic foci located in the gastrointestinal and genitourinary tracts (2,5,11). Cephalosporins and aminoglycosides are practically inactive against B. fragilis, which also has the reputation-of being relatively resistant to ampicillin and carbenicillin.…”

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confidence: 99%

Speed of Bactericidal Action of Penicillin G, Ampicillin, and Carbenicillin on Bacteroides fragilis

Schoutens

Yourassowsky

1974

Antimicrob Agents Chemother

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In order to determine the therapeutic value of penicillins in the management of anaerobic infections caused by Bacteroides fragilis, the antibacterial activity of penicillin G, ampicillin, and carbenicillin against 10 strains of B. fragilis subsp. fragilis, isolated from clinical material, was studied. This was undertaken by using a triple-layer technique, enzymatic inactivation of the antibiotics, and an automatic colony counter, which allowed a quantitative and a qualitative approach to the problem. Results indicated in vitro bactericidal activity with 40 ,

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Anaerobic bacteria isolated from decubitus ulcers

Cited by 16 publications

References 7 publications

Topical Metronidazole Therapy for Pressure Sores of Geriatric Patients

Topical Metronidazole Therapy for Pressure Sores of Geriatric Patients

Bacteriology of pressure ulcers in individuals with spinal cord injury: What we know and what we should know

Speed of Bactericidal Action of Penicillin G, Ampicillin, and Carbenicillin on Bacteroides fragilis

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