“…Gas, it will be observed, is not in itself a diagnostic criterion of much significance; in some cases it is absent or masked by the associated oedema, in most it is manifest only when the disease is already well advanced (14,106,143,155,261,432). Moreover, gassy wounds can occur in the absence of any clostridial infection: from the explosive effect of modern missiles (685, 833); in industrial accidents, from compressed air (269); from the activities of other organisms, of which the commonest is probably E. coli (25,87,224,261,511,526,663); or from various chemical agents, e.g., certain magnesium compounds (150, 683, 894). It may be added that SAttler (914) has recently given an excellent account of the differential diagnosis of gas in the tissues.…”