Anaerobic exercise capacity in patients with juvenile‐onset idiopathic inflammatory myopathies

Abstract

Objective. To 1) report the feasibility of an "all-out" 30-second cycling exercise test (Wingate Anaerobic Exercise Test [WAnT]) in juvenile-onset idiopathic inflammatory myopathy (JIIM) patients, 2) describe the anaerobic exercise capacity in juvenile dermatomyositis patients, and 3) determine if the anaerobic exercise capacity could be related to disease duration or disease phase. Methods. Twenty patients (age 14.13 ؎ 5.4 years) with JIIM participated in this study. All patients were able to perform the WAnT without adverse events. Results. Comparison with healthy controls revealed a -29.3 ؎ 26.58% (P ‫؍‬ 0.001) and -27.6 ؎ 25.7% (P ‫؍‬ 0.002) impairment in mean power and peak power on the WAnT, respectively. The WAnT correlated with disease phase and with knee extensor muscle strength. Conclusion. The WAnT might be a valuable adjunct next to other assessment tools in the followup of JIIM patients.

Physical (in)activity and its influence on disease-related features, physical capacity, and health-related quality of life in a cohort of chronic juvenile dermatomyositis patients

“…Therefore, we reinforce the idea that a series of tests, rather than only MMT and/or handgrip, should be applied in either clinical setting or research to sensitively assess muscle function in chronic JDM patients, with the guidance of the recently proposed core set [37]. Previous studies have shown that JDM patients often experience decreased strength and aerobic and anaerobic capacity [4][5][6]. These data were further confirmed in a chronic cohort of JDM patients, in which we showed that a supervised physical activity program was able to improve muscle strength, aerobic conditioning, disease activity, and health-related quality of life in chronic JDM patients [10], indirectly suggesting that physical inactivity could be partially implicated in the symptoms observed in JDM.…”

“…JDM patients often show chronic illness, sequelae of the disease, and poorer health-related quality of life [3]. Furthermore, most patients experience decreased muscle function, poor aerobic conditioning, and limited exercise tolerance [4][5][6].…”

Treatment of Juvenile Dermatomyositis: An Update

“…Children with IIMs are usually hypoactive leading to deconditioning and reduction in functional ability. Even when disease is well controlled, they still experience significant fatigue [127] and anaerobic-and aerobic exercise intolerance [128]. Moreover, decreased physical activity is known to be related with complications associated with a sedentary lifestyle including cardiovascular disease and obesity.…”

Juvenile dermatomyositis – analysis of the musculoskeletal system and proposed physiotherapy

“…Polega on na przesunięciu ogólnego rzutu środka ciężkości przed zablokowane w wyproście stawy kolanowe. Dzięki temu mechanizmowi możliwe staje się utrzymanie równowagi oraz stabilnej postawy wyprostowanej, przy użyciu minimalnej siły dużych grup mięśniowych [11][12][13].…”