Anaesthesia for patients with burns injuries

Langley, K.; Sim, K.

doi:10.1054/cacc.2002.0385

Cited by 9 publications

(13 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If Hb or myoglobin is in the urine, urine alkalinization is needed to prevent their deposition in the kidney. After resuscitation phase, a decrease in UO may indicate sepsis (Capan et al 1991;Lovich-Sapola 2008;Langley and Sim 2002).…”

Section: Kidney Effectsmentioning

confidence: 99%

“…Later, sepsis can decrease glucose synthesis. Acute hypoglycemia may indicate sepsis and/or acute liver failure (Capan et al 1991;Lovich-Sapola 2008;Langley and Sim 2002).…”

Section: Liver Effectsmentioning

confidence: 99%

“…Burn encephalopathy syndrome presents as lethargy, disorientation, delirium, seizures, or coma. Electrical injury can cause direct nerve injury (Capan et al 1991;Lovich-Sapola 2008;Langley and Sim 2002).…”

Section: Central Nervous System (Cns) Effectsmentioning

confidence: 99%

See 2 more Smart Citations

Blood Transfusion

2015

Encyclopedia of Trauma Care

View full text Add to dashboard Cite

show abstract

Section: Kidney Effectsmentioning

confidence: 99%

“…Later, sepsis can decrease glucose synthesis. Acute hypoglycemia may indicate sepsis and/or acute liver failure (Capan et al 1991;Lovich-Sapola 2008;Langley and Sim 2002).…”

Section: Liver Effectsmentioning

confidence: 99%

See 1 more Smart Citation

Blood Transfusion

2015

Encyclopedia of Trauma Care

View full text Add to dashboard Cite

show abstract

“…Chronic pain has multiple and often unclear origins. Neuropathic pain is one cause for this and develops secondary to nerve damage, abnormalities in nerve regeneration, and reprogramming of the central nervous system [ 17 ]. It can be frustratingly unresponsive to conventional treatment modalities.…”

Section: Management Of Painmentioning

confidence: 99%

Management of Pain in Children with Burns

Gandhi

Thomson

Lord

et al. 2010

International Journal of Pediatrics

View full text Add to dashboard Cite

Burn injuries are common in children under 10 years of age. Thermal injury is the most common mechanism of injury and scalds account for >60% of such injuries. All children with burns will experience pain, regardless of the cause, size, or burn depth. Undertreated pain can result in noncompliance with treatment and, consequently, prolonged healing. It is acknowledged that the monitoring and reporting of pain in children with burns has generally been poor. Due to the adverse physiological and emotional effects secondary to pain, adequate pain control is an integral and requisite component in the management of children with burns. A multidisciplinary approach is frequently necessary to achieve a robust pain relief. Key to successful treatment is the continuous and accurate assessment of pain and the response to therapy. This clinical review article discusses the essential aspects of the pathophysiology of burns in children provides an overview of pain assessment, the salient principles in managing pain, and the essential pharmacodynamics of commonly used drugs in children with burn injuries. Both pharmacological and nonpharmacological treatment options are discussed, although a detailed review of the latter is beyond the scope and remit of this article.

show abstract

“…Debridement of burn wounds and skin graft harvesting is associated with increased peri-operative bleeding, particularly in cases where the percentage of total body surface area burnt is high. These surgeries maybe associated with blood loss significant enough to warrant transfusion of blood products [1]. It is important that we use blood and blood components judiciously, since they are an expensive and a limited resource.…”

Section: Introductionmentioning

confidence: 99%

Impact of single dose intravenous tranexamic acid on peri-operative blood transfusion requirements in burn patients: A prospective, randomized trial

Bhatia

Sen

Kumari

et al. 2017

Egyptian Journal of Anaesthesia

View full text Add to dashboard Cite

Objective: Debridement of burn wounds and skin graft harvesting is associated with increased perioperative bleeding. In this study we evaluated the effectiveness of tranexamic acid in reducing blood transfusion requirements during burn wound debridement/eschar removal and skin graft harvesting in adults with major burn injuries, with the primary outcome being the total amount of intraoperative blood loss. Methods: Fifty adult patients having >20% total body surface area of burn wounds, scheduled for wound debridement/eschar removal ± skin grafting after 10 days of burn injury under general anaesthesia were included. Patients were randomly allocated to receive either injection tranexamic acid 15 mg/kg diluted to 25 ml with isotonic saline over 10 min or an equal volume of only isotonic saline before induction of general anaesthesia. Venous blood gas analysis was done in the beginning and end of surgery, and then at 24 postoperative hours to assess hemoglobin levels of the patients. Blood transfusion was given when hemoglobin levels fell down to or below 7 gm/dl. Intraoperative blood loss was calculated using the Gross formula. Results: Intraoperative blood loss was found to be significantly higher in placebo group compared to tranexamic group, 990 ± 358.9 ml vs 581 ± 333.2 ml (p < 0.00), with more blood and colloid solutions being used to replace the blood loss in placebo group (p < 0.05). Conclusions: Preoperative administration of a single dose of tranexamic acid significantly reduces blood loss during debridement of burn wounds and skin graft harvesting surgeries without increasing the risk of untoward side-effects or complications.

show abstract

Anaesthesia for patients with burns injuries

Cited by 9 publications

References 19 publications

Blood Transfusion

Blood Transfusion

Management of Pain in Children with Burns

Impact of single dose intravenous tranexamic acid on peri-operative blood transfusion requirements in burn patients: A prospective, randomized trial

Contact Info

Product

Resources

About