Anaesthetic Efficacy of 4% Articaine Mandibular Buccal Infiltration Compared To 2% Lignocaine Inferior Alveolar Nerve Block in Children with Irreversible Pulpitis

Anaesthetic efficacy of articaine versus lidocaine in children's dentistry: a systematic review and meta‐analysis

“…Two of the six included studies were multicentre studies, with the rest being conducted as single centres studies (Table ). A cross‐over design was utilised for three of six studies. Only two studies compared LA given as infiltration anaesthesia against each other, whereas four studies compared Inferior Dental Nerve (IDN) block and infiltration anaesthesia in the same study.…”

“…The age range of subjects was wide across studies (range: 5–16 years), with all subjects being 16 years of age and younger. The reported mean ages were variable, of which three studies did not report the mean ages of subjects.…”

“…The dosage and amounts of the two LA agents used were not uniform across studies. Only two studies compared equivalent concentrations of articaine and lidocaine, whereas the others had variable amounts administered to the child in which the maximum dose was calculated per body weight.…”

“…Only three studies reported evaluating onset time of anaesthesia, in which one study categorised the onset time, whereas two other studies reported the mean onset time. Methods for evaluation of onset time were mostly subjective evaluations by patients, with two studies evaluating the onset by asking the child when the sensation of soft tissue numbness started, and one paper did not detail the method used for evaluation of anaesthesia onset. The delay in time for checking of anaesthesia onset varied between studies (from 2 to 5 min after LA delivery).…”

“…Among the studies included in the review, evaluation of anaesthetic efficacy was largely carried out in the treatment phase of the study. Only two studies reported on patient's pain during the injection phase.…”