Anal intercourse: a risk factor for anal papillomavirus infection in women?

Law, Carmella; Thompson, Carol H.; Rose, Barbara; Cossart, Yvonne E.

doi:10.1136/sti.67.6.464

Cited by 6 publications

(5 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of this study were similar to those of other studies that have not found any association between anal HPV infection and anal intercourse [Law et al, 1991; Moscicki et al, 2003], which may suggest alternative transmission routes, including sexual and nonsexual routes [Winer et al, 2003]. The trauma associated with anal intercourse is a risk factor for the cytological abnormalities caused by the virus.…”

Section: Discussionsupporting

confidence: 90%

Prevalence of abnormal anal cytology in women infected with HIV

Chaves

Folgierini

Capp

et al. 2012

Journal of Medical Virology

View full text Add to dashboard Cite

Anal cancer is a rare disease. Nevertheless, it may be a reason for concern among groups in which its incidence is increasing: those who engage in anoreceptive intercourse, promiscuous persons, and those with sexually transmitted infections (HPV and HIV). The aim of this study was to evaluate the prevalence of abnormal anal cytology in women infected with HIV seen at Hospital de Clínicas de Porto Alegre, Brazil. A cross-sectional design was used. Anal smear screening was offered to all women infected with HIV seen at the hospital's outpatient sexually transmitted infections clinic from March 2006 to March 2008. A total of 184 patients were thus enrolled. Only patients who gave written consent were included in the study. The prevalence of abnormal anal cytology was 14.1% (26 patients). Twenty-two patients presented atypical squamous cells of undetermined significance, and four exhibited low-grade intraepithelial neoplasia. Initially, abnormal anal cytology was significantly associated with age, number of pregnancies, smoking, abnormal cervical cytology, CD4⁺ < 200 cells/mm³ and hepatitis C co-infection. After adjustment, only CD4⁺ < 200 cells/mm³ and smoking were found to increase the risk of altered anal cytology. The anal Pap method described is simple and can be used for screening in cohorts of HIV-positive women who are at risk of developing anal carcinoma, mainly those with CD4⁺ counts <200 cells/mm³ and smokers.

show abstract

Section: Discussionsupporting

confidence: 90%

Prevalence of abnormal anal cytology in women infected with HIV

Chaves

Folgierini

Capp

et al. 2012

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

“…Hosseini et al, (2018) showed that the patients who had anal intercourse showed more positive anal cytology than those who did not significantly. However some studied reported no association between anal intercourse and the presence of anal HPV infection (Law et al, 1991). In our study, case of AIN 3 had never had anal intercourse.…”

Section: Discussioncontrasting

confidence: 53%

Prevalence of Abnormal Anal Cytology in Women with Abnormal Cervical Cytology

Inthasorn

Wetpithayakom

Laiwejpithaya

et al. 2021

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Objective: The aim of this study was to evaluate the prevalence of abnormal anal cytology in women presenting with abnormal cervical cytology (intraepithelial lesion or cervical cancer) at the largest tertiary university hospital in Thailand. Methods: A cross-sectional prospective study design was used. Anal cytology was performed on 145 women with abnormal cervical cytology between June 2014-Octoble 2014. If abnormal anal cytology was detected, anoscopy was performed with biopsy in any suspicious area of precancerous change. Results: Prevalence of abnormal anal cytology was 5.5% (8 patients). Of 8 patients, six patients presented with low-grade squamous intraepithelial lesion, one patient with high-grade squamous intraepithelial lesion, and one with atypical squamous cell cannot exclude highgrade squamous intraepithelial lesion. Abnormal anoscopic impression was found in 3 cases, as follow: The first case showed faint acetowhite lesion and anoscopic impression was low grade squamous intraepithelial lesion; the second case was reported as human papillomavirus (HPV) change by anoscopic impression; and the third case showed dense acetowhite lesion with multiple punctation and pathologic examination showed anal intraepithelial neoplasm III (AIN3). The last patient underwent wide local excision of AIN3 with split-thickness skin graft reconstruction. Final pathology confirmed AIN3 with free resection margin. Conclusion: Prevalence of abnormal anal cytology was 5.5% in patients with abnormal cervical cytology. The prevalence might be support anal cytology screening in this group of patients.

show abstract

“…Information related to other risk factors, such as race/ethnicity, sexual activity/history, and socio-economic status were not available for study [8]. Research has shown that certain types of sexual behavior increase the risk of genital HPV infection and anal cancer, such as having sex at an early age, having multiple sexual partners, sexual orientation, and participating in receptive anal intercourse [8,27].…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Anal Dysplasia among Privately Insured HIV-Negative Women

Rodrı́guez¹,

Rodríguez²,

Ye³

et al. 2017

J Cancer Res Immunooncol

View full text Add to dashboard Cite

Objective: To examine the relationship between anogenital abnormalities and the development of anal dysplasia among Human Immunodeficiency Virus (HIV)-negative women. Methods:This retrospective matched case-control study used administrative data from the 2009-2014 Clinformatics Data Mart. Cases were selected according to the International Classification of Diseases, Ninth Revision, using Clinical Modification codes for carcinoma in situ of the anal canal or anus unspecified, anal intraepithelial neoplasia 1 and 2, abnormal glandular Papanicolaou (Pap) smear of the anus, or Pap smears of the anus with atypical squamous cells, squamous intraepithelial lesions, or cytological evidence of malignancy. Conditional logistic regression analysis was used to calculate odds ratios (ORs) and 95% confidence intervals for the risk of anal dysplasia. Results:The study included 3,384 HIV-negative women (846 cases and 2,538 controls), mean age 50.1 ± 11.9 years. The odds of being a smoker, having cervical intraepithelial neoplasia (CIN), or anogenital warts were higher for HIV-negative women with anal dysplasia than for those without anal dysplasia (OR =2.5-16.3). Conclusions:HIV-negative women with anal dysplasia are more likely to have concomitant human papillomavirus (HPV)-related CIN and anogenital warts than women without anal dysplasia. The presence of HPV-associated lesions might have implications for future screening recommendations. HIV-negative women with a history of CIN and anogenital warts could benefit from anal dysplasia/anal cancer screening. Gaining a better understanding of the natural history of anal HPV infections will provide tools to better treat and counsel patients with anal dysplasia. MeasuresAge, gender, and region were obtained from the member files. Using claims for medical services in the 3 years before the event/index Figure 1: Flow chart depicting the selection process for cases (left) and controls (right) included in the present stu.

show abstract

Anal intercourse: a risk factor for anal papillomavirus infection in women?

Abstract: Objective-To determine whether anal intercourse is a risk factor for anal HPV infection in women.Design

Cited by 6 publications

References 14 publications

Prevalence of abnormal anal cytology in women infected with HIV

Prevalence of abnormal anal cytology in women infected with HIV

Prevalence of Abnormal Anal Cytology in Women with Abnormal Cervical Cytology

Risk Factors for Anal Dysplasia among Privately Insured HIV-Negative Women

Contact Info

Product

Resources

About