Analgesia following appendicectomy — the value of peritoneal bupi-vacaine

Colbert, S.; O’Hanlon, Deirdre; Courtney, D.; Quill, Denis; Flynn, Noel M.

doi:10.1007/bf03012142

Cited by 13 publications

(7 citation statements)

References 22 publications

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“…In another study, 17 10 ml 2% lidocaine was administered peritoneally, and it was reported that this too provided effective analgesia. Some other studies have shown similar results 16–23 …”

Section: Discussionsupporting

confidence: 67%

The analgesic efficacy of intraperitoneal local anaesthetic instillation after laparoscopic gynaecological procedures

et al. 2002

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Objective Patients undergoing laparoscopic procedures may experience postoperative pain. We evaluated the effectiveness of intraperitoneal local anaesthetic instillation after laparoscopic gynaecological procedures. Design Randomized, double‐blinded, placebo‐controlled trial. Methods Patients were randomly assigned to one of three groups of 20 patients each. Those in group A received ropivacaine, 20 ml 0.75%, and those in group B received bupivacaine, 20 ml 0.5% intraperitoneally. Those in group C (the control group) received 20 ml 0.9% saline. Pain was assessed, using a visual analogue scale (VAS) and a verbal rating scale (VRS), at 30 min, 60 min, 2 h and 4 h after surgery. Total analgesic consumption and the time to first need for analgesia were also noted. Results VAS and VRS pain scores were significantly lower in the ropivacaine and bupivacaine groups compared with the placebo group. Patients in group A (ropivacaine) experienced less pain than those in group B (bupivacaine) for all measurements. The time to first need for analgesia was significantly later for the ropivacaine and bupivacaine groups compared with the placebo group. The total analgesic consumption was also significantly lower in those groups than in the placebo group. Conclusion The results indicated that both ropivacaine and bupivacaine were effective at preventing pain and the need for postoperative analgesic when intraperitoneally instilled. However, ropivacaine is the better choice because of its higher efficacy.

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Section: Discussionsupporting

confidence: 67%

The analgesic efficacy of intraperitoneal local anaesthetic instillation after laparoscopic gynaecological procedures

et al. 2002

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“…Pain was assessed in seven RCTs 34–40 . However, only six trials compared IPLA with placebo or no IPLA as one trial was a dose finding study 40 .…”

Section: Resultsmentioning

confidence: 99%

Intraperitoneal local anaesthetic in abdominal surgery – a systematic review

Kahokehr

Sammour

Soop

et al. 2010

ANZ Journal of Surgery

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“…Other authors have emphasized the importance of peritoneal irritation in postoperative pain rather than pain from the abdominal wall musculature. A randomized trial comparing combined bupivacaine infiltration to the peritoneum and the skin compared with skin alone after appendicectomy did show lower pain scores at 30 min and lower analgesic use in the first 24 h postoperatively [5].…”

Section: Discussionmentioning

confidence: 99%