Analgesia in patients with or without single-shot lamina thoracic paravertebral block following breast cancer surgery in a Nigerian hospital

Rukewe, Ambrose; Ademola, A. Ladele; Fatiregun, AA; Ugheoke, A

doi:10.4314/ecajs.v21i1.139052

East. Cent. Afr. J. Surg.

2016

DOI: 10.4314/ecajs.v21i1.139052

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Analgesia in patients with or without single-shot lamina thoracic paravertebral block following breast cancer surgery in a Nigerian hospital

Ambrose Rukewe¹,

A. Ladele Ademola²,

AA Fatiregun³

et al.

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2021

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Analgesic and Opioid Sparing Effects of Preoperative Thoracic Paravertebral Block

Okoye¹,

Majekodunmi²,

Ilori³

2021

Nigerian Postgraduate Medical Journal

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Background: Various regional anaesthetic techniques are used for post-mastectomy pain relief; however, thoracic paravertebral block (TPVB) has shown some advantages over other methods. This study sought to demonstrate the post-operative benefit of pre-operative TPVB in patients scheduled for simple mastectomy. Methods: The study was carried out on 60 adult female patients with the American Society of Anesthesiologists physical status Class I to III scheduled for unilateral mastectomy. Pre-operatively, a nerve stimulator was used to locate the paravertebral space thereafter bupivacaine with adrenaline or saline was injected into the space. Post-operatively, intravenous morphine patient controlled analgesia was commenced in the two groups for 24 h after the surgery. In addition, intravenous paracetamol 15 mg/kg was administered 6 hourly for 24 h in both groups. Results: The 24 h morphine consumption was significantly reduced in the bupivacaine group compared to the control group (P = 0.000). The Numerical pain rating score was significantly lower in the bupivacaine group than in the control group in the 1st 6 h; P = 0.001. The time to first request for analgesia was significantly longer in the bupivacaine group than the control group (P = 0.000). Nausea was the major side effect detected and this was significantly higher in the control group (P = 0.024). The morphine sparing effect was 65.7% in the bupivacaine group. Conclusion: The study showed that bupivacaine-based TPVB provided an effective post-operative analgesic and opioid-sparing effect for simple mastectomy when compared with a saline-based control group that received only intravenous morphine patient controlled analgesia and paracetamol.

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Analgesic and Opioid Sparing Effects of Preoperative Thoracic Paravertebral Block

Okoye¹,

Majekodunmi²,

Ilori³

2021

Nigerian Postgraduate Medical Journal

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Analgesia in patients with or without single-shot lamina thoracic paravertebral block following breast cancer surgery in a Nigerian hospital

Cited by 1 publication

References 13 publications

Analgesic and Opioid Sparing Effects of Preoperative Thoracic Paravertebral Block

Analgesic and Opioid Sparing Effects of Preoperative Thoracic Paravertebral Block

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