Analgesia Nociception Index for perioperative analgesia monitoring in spinal surgery

Turan, Güldem; Ar, Arzu Yıldırım; Kuplay, Yıldız Yiğit; Demiroluk, Öznur; Gazi, Mustafa; Akgün, Nur; Çelikoğlu, Erhan

doi:10.1016/j.bjane.2016.07.010

Cited by 15 publications

(35 citation statements)

References 10 publications

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“…The ANI is commonly thought of as a numerical and objective indicator of perioperative analgesia levels [15], although some authors have suggested that potential hemodynamic changes can be predicted based on perioperatively monitored ANI values [16], while there have been further studies reporting the contrary [12,18,19]. Overall, almost all of those studies indicated that the ANI values may be in line with clinical status, even during spontaneous respiration in sedated patients under the influence of anesthesia [17][18][19].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, some studies tested the use of the ANI to detect the level of analgesia in pediatric patients, and the results of such preliminary studies were found to be positive [20,21]. Extending these general considerations, some authors argued that the severity of potential postoperative pain can be measured objectively based on the ANI values recorded at the end of the perioperative period [13], and even that the level of pain can be predicted based on these values, therefore allowing the early identification of severe pain risk and the making of effective interventions accordingly [14,15].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Based on this index, values of 50 and above indicate sufficient anesthesia, 30-50 indicate moderate pain, and values lower than 30 indicate severe pain [9][10][11][12]. Over the last few years, researchers have reported preliminary findings suggesting that the severity of potential postoperative pain can be predicted objectively, irrespective of the physician's subjective assessment, based on ANI values recorded immediately after surgery [13], and these data may even allow the prediction of the severity of early postoperative pain [14,15].…”

Section: Introductionmentioning

confidence: 99%

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Can postoperative pain be predicted? New parameters; Analgesia nociception index

Köprülü

Haspolat

Gül³

et al. 2020

Turk J Med Sci

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Background/aim: The Analgesia Nociception Index (ANI) is a new method of identifying nociception-analgesia balance. In this study, we investigate the correlation between the ANI and numeric rating scale (NRS) values immediately before and after extubation. The NRS values were recorded in the postanesthesia care unit, in a group of patients who underwent laparoscopic cholecystectomy, with the aim of evaluating the potential use of ANI values in the prediction of postoperative pain levels. Materials and methods: The ANI and NRS values, heartbeat rate (HR), systolic and diastolic arterial pressure (SAP/DAP), and oxygen saturation (SpO 2) values of the patients were recorded into three groups based on the initial NRS values recorded in the postanesthesia care unit (group I: NRS ≤ 3, group II: NRS 4-6, group III: NRS ≥ 7). Patients whose ANI values were lower than 47, considered as the pain threshold, and the groups to which these patients belonged were also recorded. Results: Statistically significant increases were noted in HR, SAP, and DAP after extubation, while there was no significant change in ANI values. A weak correlation was identified between the ANI and NRS values of all patient groups. Conclusion: We failed to identify a correlation between ANI and NRS values before and after extubation. Previous studies suggested that the ANI provides more valuable information in anesthetized patients, whereas our findings show that it is ineffective in the prediction of potential postoperative pain.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Can postoperative pain be predicted? New parameters; Analgesia nociception index

Köprülü

Haspolat

Gül³

et al. 2020

Turk J Med Sci

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“…A value ≥50 indicates adequate analgesia [6,7]. Several studies have shown that ANI could be used to predict immediate postoperative pain [8], guide intraoperative opioid administration [5,9,10], and predict the need for analgesia during the early postoperative period [11]. Even though the ideal method for optimizing opioid administration is to follow the pharmacokinetic pattern in order to maintain a serum concentration above the therapeutic level, this method is not practicable.…”

Section: Introductionmentioning

confidence: 99%

Comparative study of analgesia nociception index (ANI) vs. standard pharmacokinetic pattern for guiding intraoperative fentanyl administration among mastectomy patients

et al. 2021

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Background The Analgesia Nociception Index (ANI) has been suggested as a non-invasive guide for analgesia. Our objective was to compare the efficacy of ANI vs. standard pharmacokinetic pattern for guiding intraoperative fentanyl administration. Methods This was a prospective, randomized, controlled study of adult female patients undergoing elective mastectomy under general anesthesia. The patients were randomized to the ANI-guided group receiving a loading dose of 75 μg of fentanyl followed by 25 μg when the ANI score was under 50. The Control group received the same loading dose followed by 25 μg every 30 min with additional doses when there were signs of inadequate analgesia (viz., tachycardia or hypertension). Results Sixty patients—30 in each group—were recruited. Although the actual mean ANI score was higher in the ANI-guided than in the Control group (mean difference 2.2; 95% CI: 0.3 to 4.0, P = 0.022), there was no difference in the primary outcome—i.e., intraoperative fentanyl consumption (mean difference − 4.2 μg; 95% CI: − 24.7 to 16.4, P = 0.686 and − 0.14 μg·kg− 1·h− 1; 95% CI: − 0.31 to 0.03, P = 0.105). No difference between groups was shown for either intraoperative blood pressure and heart rate, or for postoperative outcomes (i.e., pain scores, morphine consumption, or sedation scores) in the postanesthesia care unit. Conclusions Intraoperative fentanyl administration guided by ANI was equivalent to that guided by a modified pharmacologic pattern. In a surgical model of mastectomy, the ANI-guided intraoperative administration of fentanyl had no impact on clinical outcomes. Trial registration The study was registered with ClinicalTrials.gov (NCT03716453) on 21/10/2018.

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Guiding opioid-free intravenous antinociception with the Analgesia Nociception Index: a case report

Coeckelenbergh

Estèbe

2020

Brazilian Journal of Anesthesiology (English Edition)

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Analgesia Nociception Index for perioperative analgesia monitoring in spinal surgery

Cited by 15 publications

References 10 publications

Can postoperative pain be predicted? New parameters; Analgesia nociception index

Can postoperative pain be predicted? New parameters; Analgesia nociception index

Comparative study of analgesia nociception index (ANI) vs. standard pharmacokinetic pattern for guiding intraoperative fentanyl administration among mastectomy patients

Guiding opioid-free intravenous antinociception with the Analgesia Nociception Index: a case report

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