Analgesic effect of non-nutritive sucking in term neonates: A randomized controlled trial

Vu-Ngoc, Hai; Uyen, Nguyen Cao Minh; Thinh, Ong Phuc; Don, Le Duc; Danh, Nguyen Vo Tan; Truc, Nguyen Tran Thanh; Tuong, Vu Thi; Vuong, Nguyen Lam; Huy, Nguyen Tien; Duong, Pham Diep Thuy

doi:10.1016/j.pedneo.2019.07.003

Cited by 27 publications

(24 citation statements)

References 36 publications

(40 reference statements)

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“…A strong, statistically significant (p-value <0.01) positive correlation was seen between the pain scores on the N-PASS and the other two scales-NFCS and NIPS. Also, Vu-Ngoc H et al [12] suggested NNS be a secure and effective pain-relieving method in term neonates when performing heelprick. In another similar study, there were no statistically significant differences in heart rate or SpO2 between the treatment group (TG) [oral 1 mL 24% sucrose] and the control group (CG) [oral 1 mL 10% glucose) before venipuncture.…”

Section: Discussionmentioning

confidence: 99%

Effect of Vibratory Therapy in Decreasing the Vaccination-induced Pain in Infants: Randomized Controlled Study

Taksande

Panwar

Jhamb

et al. 2021

JPRI

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Background: Different non-medical therapies such as Non-nutritive sucking (NNS), oral sucrose with or without NNS (non-nutritive sucking), wrapping with thin blanket or cloth, kangaroo mother care (KMC), songs as well as multi-sensory stimulation are beneficial in pain reduction among neonates and infants. According to the gate control theory, vibrations applied sat a site on the body block the nociceptive signals via the A???? and C fibers reducing the pain perception. When used along with many other nonpharmacological methods, This technique has been shown to minimize discomfort in pain-inducing treatments such as Intravenous cannulation, vaccines, heel prick, etc. The primary purpose of this study is to analyze vibrational therapy effects on infants pain perception, thereby, providing evidence for a better pain management strategy in vaccination centers. Objective: To determine the efficacy of vibration therapy on pain perception by infants during vaccine administration. Material and Methods: Out of total 90 eligible healthy infants who come for routinely immunization will be given either vibrational therapy (interventional group) or breastfeeding(control therapy) after doing randomization in this randomized controlled trial. The baseline vitals include cardiac rate (HR), respiratory rate (RR), and oxygen (SpO2) will be recorded before, during, and after vaccination during this treatment. Similarly, we will report Visual analog scales (VAS), Neonatal Infant Pain Scale (NIPS), and Wong-Baker FACES Pain Rating Scale, Modified Behavioral Pain Scale (MBPS) after giving the vaccine to the infant. Results: After completion of the study we will come to know the effect of vibratory therapy on pain control. The pain intensity with the help of the NIPS score will get less in the vibratory group than in the control group. The level of distress by using the Color Analogue Scale, MBPS scale, and FLACC scale, during the vaccine-related procedure will get a lower score in the infants who has taken vibratory therapy than the control group. Conclusion: study will probably give us information about vibration therapy, which will be an effective method for managing the pain after vaccination in infants.

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Section: Discussionmentioning

confidence: 99%

Effect of Vibratory Therapy in Decreasing the Vaccination-induced Pain in Infants: Randomized Controlled Study

Taksande

Panwar

Jhamb

et al. 2021

JPRI

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“…N-PASS was used to measure acute (e.g., procedural) pain in all neonatal gestational age categories as defined by WHO, including extremely preterm (n = 5) [17][18][19][20][21], very preterm (n = 5) [17,18,[21][22][23], late preterm (n = 5) [10,11,17,21,24], and term infants (n = 7) [17,21,[25][26][27][28][29]. N-PASS was also used to measure acute pain in infants age 1-36 months (n = 1) [30].…”

Section: Acute Painmentioning

confidence: 99%

“…In addition to variation observed by gestational age group and clinical setting, N-PASS was used to measure acute pain in neonatal subpopulations including mechanically ventilated infants (n = 6) [10,11,[18][19][20][21], nonmechanically ventilated infants (n = 8) [18,20,21,23,[27][28][29]32], and postoperative infants (n = 2) [30,32].…”

Section: Acute Painmentioning

confidence: 99%

Neonatal Pain, Agitation, and Sedation Scale’s use, reliability, and validity: a systematic review

et al. 2020

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The Neonatal Pain, Agitation, and Sedation Scale (N-PASS) is recommended by the American Academy of Pediatrics to measure neonatal pain and sedation. However, little is known regarding its reliability and validity for diverse neonatal subpopulations. Twenty-nine studies were included in our review, demonstrating broad application of N-PASS and good or excellent reliability and validity for various neonatal subpopulations. Our systematic review found N-PASS to be valid and reliable for many but not all neonatal subpopulations. There is a lack of support for N-PASS reliability and validity for measuring prolonged pain and sedation in nonmechanically ventilated infants and for acute pain in postoperative infants in any gestational age category. Overall, N-PASS is a psychometrically sound and pragmatic instrument evaluating pain and sedation for most neonatal populations. Future research using N-PASS is encouraged to evaluate and report its validity and reliability, especially for neonatal subpopulations not included in this review.

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“…Many studies have been performed to find the best non-pharmacological way to reduce pain in infants, which mainly include skin-to-skin contact, Kangaroo Mother Care (KMC), tucking by parents, glucose solutions such as dextrose, non-nutritive sucking in term neonates, and breastfeeding [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ]. It is assumed that breastfeeding reduces pain sensations through three different mechanisms: endorphin release due to the sweet taste, skin contact and cradling during breastfeeding and the sucking reflex.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Methods to Minimize Pain in Newborns during Capillary Blood Sampling for Screening: A Randomized Clinical Trial

Napiórkowska-Orkisz

Gutysz-Wojnicka

Tanajewska

et al. 2022

IJERPH

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Aim: The aim of the study was to assess the severity of pain experienced by a newborn during a heel puncture for screening using the Newborn Pain Scale (NIPS), measure the heart rate and compare the effectiveness of non-pharmacological methods of pain control. Design: Randomized clinical trial. No experimental factors. The test was performed during routine screening. Surroundings: Provincial Specialist Hospital in Olsztyn. Patients/Participants: Pain was assessed in 90 full-term newborns. The newborns were rooming in with their mothers in the hospital. Interventions: Newborns were divided into three groups. Three different methods of pain relief were used: breastfeeding, 20% glucose administered orally and non-nutritional sucking. Main Outcome Measures: The primary pain outcome was measured using the NIPS and the secondary pain outcome measures (heart rate, oxygen saturation) were measured using a pulse oximeter. Results: During capillary blood sampling from the heel, most newborns, n = 56 (62.2%), experienced no pain or mild discomfort, severe pain occurred in n = 23 (25.6%) and moderate pain occurred in n = 11 (12.2%). No significant statistical differences were found between the degree of pain intensity and the intervention used to minimize the pain p = 0.24. Statistically significant relationships were demonstrated between heart rate variability and the degree of pain intensity (p = 0. 01). There were no statistically significant differences between the newborn’s pain intensity and the mother’s opinion on the effectiveness of breastfeeding in minimizing pain. Conclusions: This study did not answer the question of which pain management method used during the heel prick was statistically more effective in reducing pain. However, the results indicate that each of the non-pharmacological interventions (breastfeeding, oral glucose dosing and non-nutritive sucking) applied during heel puncture resulted in effective pain management in most of the newborns enrolled in the study. The relationship between heart rate variability and the severity of pain was confirmed. Mothers of newborns in the breastfeeding group were satisfied with the pain relief methods used in the child and the opportunity to console their newborn during painful procedures in a technologically invasive environment.

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Analgesic effect of non-nutritive sucking in term neonates: A randomized controlled trial

Cited by 27 publications

References 36 publications

Effect of Vibratory Therapy in Decreasing the Vaccination-induced Pain in Infants: Randomized Controlled Study

Effect of Vibratory Therapy in Decreasing the Vaccination-induced Pain in Infants: Randomized Controlled Study

Neonatal Pain, Agitation, and Sedation Scale’s use, reliability, and validity: a systematic review

Evaluation of Methods to Minimize Pain in Newborns during Capillary Blood Sampling for Screening: A Randomized Clinical Trial

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