Analgesic effects of manual therapy in patients with musculoskeletal pain: A systematic review

Voogt, Lennard; Vries, J. de; Meeus, Mira; Struyf, Filip; Meuffels, Duncan E.; Nijs, Jo

doi:10.1016/j.math.2014.09.001

Cited by 111 publications

(83 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, significant relationship between reduced activation in the insular cortex and decreased subjective pain ratings were found. Finally, the systematic reviews of Coronado et al (2012) and Voogt et al (2015) reported a clear effect in favor to spinal manipulative therapy on pressure pain threshold (PPT), supporting a potential central nervous system mechanism. The results of the present analysis are partially in agreement with literature consensus regarding that hypoalgesia could be mediated by MMA.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of musculoskeletal manual approach in the treatment of temporomandibular joint disorder: A systematic review with meta-analysis

et al. 2016

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Efficacy of musculoskeletal manual approach in the treatment of temporomandibular joint disorder: A systematic review with meta-analysis

et al. 2016

View full text Add to dashboard Cite

“…The literature clearly indicates that neurophysiological responses, such as changes in pain sensitivity, are associated with manual therapy interventions. 7,19,27,28,32,48,63 However, clarification is required to better determine (1) the extent to which the specific features of the mechanical stimulus (ie, changing location of TM application) influence pain sensitivity response, and (2) the clinical relevance of the associated neurophysiological responses.…”

mentioning

confidence: 99%

The Comparative Effects of Spinal and Peripheral Thrust Manipulation and Exercise on Pain Sensitivity and the Relation to Clinical Outcome: A Mechanistic Trial Using a Shoulder Pain Model

Coronado¹,

Bialosky²,

Bishop³

et al. 2015

Journal of Orthopaedic & Sports Physical Therapy

View full text Add to dashboard Cite

STUDY DESIGN Single-blind randomized trial. OBJECTIVES To compare the effects of cervical and shoulder thrust manipulation (TM) and exercise on pain sensitivity, and to explore associations with clinical outcomes in patients with shoulder pain. BACKGROUND Experimental studies indicate that spinal TM has an influence on central pain processes, supporting its application for treatment of extremity conditions. Direct comparison of spinal and peripheral TM on pain sensitivity has not been widely examined. METHODS Seventy-eight participants with shoulder pain (36 female; mean ± SD age, 39.0 ± 14.5 years) were randomized to receive 3 treatments of cervical TM (n = 26), shoulder TM (n = 27), or shoulder exercise (n = 25) over 2 weeks. Twenty-five healthy participants (13 female; mean ± SD age, 35.2 ± 11.1 years) were assessed to compare pain sensitivity with that in clinical participants at baseline. Primary outcomes were changes in local (eg, shoulder) and remote (eg, tibialis anterior) pressure pain threshold and heat pain threshold occurring over 2 weeks. Secondary outcomes were shoulder pain intensity and patient-rated function at 4, 8, and 12 weeks. Analysis-of-variance models and partial-correlation analyses were conducted to examine comparative effects and the relationship between measures. RESULTS At baseline, clinical participants demonstrated lower local (mean difference, −1.63 kg; 95% confidence interval [CI]: −2.40, −0.86) and remote pressure pain threshold (mean difference, −1.96 kg; 95% CI: −3.09, −0.82) and heat pain threshold (mean difference, −1.15°C; 95% CI: −2.06, −0.24) compared to controls, suggesting enhanced pain sensitivity. Following intervention, there were no between-group differences in pain sensitivity or clinical outcome (P>.05). However, improvements were noted, regardless of intervention, for pressure pain threshold (range of mean differences, 0.22–0.32 kg; 95% CI: 0.03, 0.43), heat pain threshold (range of mean differences, 0.30–0.58; 95% CI: 0.06, 0.96), pain intensity (range of mean differences, −1.79 to −1.45; 95% CI: −2.34, −0.94), and function (range of mean differences, 3.15–3.82; 95% CI: 0.69, 6.20) at all time points. We did not find an association between pain sensitivity changes and clinical outcome (P>.05). CONCLUSION Clinical participants showed enhanced pain sensitivity, but did not respond differently to cervical or peripheral TM. In fact, in this sample, cervical TM, shoulder TM, and shoulder exercise had similar pain sensitivity and clinical effects. The lack of association between pain sensitivity and clinical pain and function outcomes suggests different (eg, nonspecific) pain pathways for clinical benefit following TM or exercise.

show abstract

“…Congruent information processing could have inhibited habitual pain in the present population. The analgesic effects of manual therapy are not fully understood (Vigotsky and Bruhns, 2015;Voogt et al, 2015). Recent reviews emphasize the role of spinal and supraspinal structures, which are triggered by manual therapy, in inhibiting pain responses in the peripheral and central nervous system (Bialosky et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Seeing the site of treatment improves habitual pain but not cervical joint position sense immediately after manual therapy in chronic neck pain patients

Beinert

Lutz

Zieglgänsberger

et al. 2018

European Journal of Pain

View full text Add to dashboard Cite

show abstract

Analgesic effects of manual therapy in patients with musculoskeletal pain: A systematic review

Cited by 111 publications

References 28 publications

Efficacy of musculoskeletal manual approach in the treatment of temporomandibular joint disorder: A systematic review with meta-analysis

Efficacy of musculoskeletal manual approach in the treatment of temporomandibular joint disorder: A systematic review with meta-analysis

The Comparative Effects of Spinal and Peripheral Thrust Manipulation and Exercise on Pain Sensitivity and the Relation to Clinical Outcome: A Mechanistic Trial Using a Shoulder Pain Model

Seeing the site of treatment improves habitual pain but not cervical joint position sense immediately after manual therapy in chronic neck pain patients

Contact Info

Product

Resources

About