Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following open major hepatectomy: an open-label, randomised, controlled, non-inferiority trial

Wang, Danfeng; Liao, Chengyu; Tian, Yifeng; Zheng, Ting; Ye, Huazhen; Yu, Zenggui; Jiang, Jundan; Su, Jiawei; Chen, Shi; Zheng, Xiaochun

doi:10.1016/j.eclinm.2023.102188

eClinicalMedicine

2023

DOI: 10.1016/j.eclinm.2023.102188

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Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following open major hepatectomy: an open-label, randomised, controlled, non-inferiority trial

Danfeng Wang,

Chengyu Liao,

Yifeng Tian

et al.

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2024

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Cited by 4 publications

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Letter regarding ‘Development of a nomogram for predicting acute pain among patients after abdominal surgery: A prospective observational study’

Pan,

Zheng

2024

Journal of Clinical Nursing

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Letter regarding ‘Development of a nomogram for predicting acute pain among patients after abdominal surgery: A prospective observational study’

Pan,

Zheng

2024

Journal of Clinical Nursing

Self Cite

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A proof-of-concept study of ultrasound-guided continuous parasacral ischial plane block for postoperative pain control in patients undergoing total knee arthroplasty

Ye,

Zheng,

Gong

et al. 2024

J Orthop Surg Res

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Background Continuous peripheral nerve blocks are widely used for anesthesia and postoperative analgesia in lower limb surgeries. The authors aimed to develop a novel continuous sacral plexus block procedure for analgesia during total knee arthroplasty. Methods The study comprised two stages. In Stage I, the authors built upon previous theories and technological innovations to develop a novel continuous sacral plexus block method, ultrasound-guided continuous parasacral ischial plane block (UGCPIPB) and subsequently conducted a proof-of-concept study to assess its effectiveness and feasibility. Stage II involved a historical control study to compare clinical outcomes between patients undergoing this new procedure and those receiving the conventional procedure. Results The study observed a 90% success rate in catheter placement. On postoperative day (POD) 1, POD2, and POD3, the median visual analog scale (VAS) scores were 3 (range, 1.5–3.5), 2.5 (1.6–3.2), and 2.7 (1.3–3.4), respectively. Furthermore, 96.3% of the catheters remained in place until POD3, as confirmed by ultrasound. The study revealed a significant increase in skin temperature and peak systolic velocity of the anterior tibial artery on the blocked side compared with those on the non-blocked side. Complications included catheter clogging in one patient and leakage at the insertion site in two patients. In Stage II, the novel technique was found to be more successful than conventional techniques, with a lower catheter displacement rate than the conventional procedure for continuous sciatic nerve block. Conclusion UGCPIPB proved to be an effective procedure and safe for analgesia in total knee arthroplasty. Chinese Clinical Trial Registry Number ChiCTR2300068902.

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Continuous bilateral erector spinae plane block for open hepatectomy

TOSCANO,

CREMASCOLI,

BALZANO

et al. 2024

Minerva Anestesiol

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Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following open major hepatectomy: an open-label, randomised, controlled, non-inferiority trial

Cited by 4 publications

References 55 publications

Letter regarding ‘Development of a nomogram for predicting acute pain among patients after abdominal surgery: A prospective observational study’

Letter regarding ‘Development of a nomogram for predicting acute pain among patients after abdominal surgery: A prospective observational study’

A proof-of-concept study of ultrasound-guided continuous parasacral ischial plane block for postoperative pain control in patients undergoing total knee arthroplasty

Continuous bilateral erector spinae plane block for open hepatectomy

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