1986
DOI: 10.1002/j.1875-9114.1986.tb03494.x
|View full text |Cite
|
Sign up to set email alerts
|

Analgesic Efficacy of Low‐dose Ibuprofen in Dental Extraction Pain

Abstract: A single-dose, double-blind, randomized, parallel trial was conducted to compare the analgesic efficacy of oral ibuprofen (I) 100, 200, or 400 mg, aspirin (ASA) 650 mg, and placebo in moderate to severe pain after extraction of impacted teeth. Subjective, self-evaluated pain intensity and pain relief reports, hourly for 6 hours, were used as indexes of analgesic response. Data on 227 evaluable patients showed significant differences among the 4 active treatments and placebo (p less than 0.001) by most measurem… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
17
0

Year Published

1999
1999
2024
2024

Publication Types

Select...
4
2

Relationship

0
6

Authors

Journals

citations
Cited by 43 publications
(18 citation statements)
references
References 7 publications
1
17
0
Order By: Relevance
“…[11][12][13][14][15][16][17][18] Most of these studies examine the effect of ibuprofen up to 6 hours after surgery whereas this study examines whether Ibuprofen 400 mg three times a day provides good pain relief over a 48-hour period after surgery. Taking an acceptable score of pain relief as 2 or less, ibuprofen appeared to effectively control pain in 137 patients (85%), but 42 patients had self-prescribed paracetamol or a combination paracetamol as supplemental analgesia.…”
Section: Discussionmentioning
confidence: 99%
“…[11][12][13][14][15][16][17][18] Most of these studies examine the effect of ibuprofen up to 6 hours after surgery whereas this study examines whether Ibuprofen 400 mg three times a day provides good pain relief over a 48-hour period after surgery. Taking an acceptable score of pain relief as 2 or less, ibuprofen appeared to effectively control pain in 137 patients (85%), but 42 patients had self-prescribed paracetamol or a combination paracetamol as supplemental analgesia.…”
Section: Discussionmentioning
confidence: 99%
“…Eleven studies had 40 or more participants in both treatment arms Forbes 1991a;Hersch 1993b;Jain 1986;Kiersch 1993;Medve 2001;Mehlisch 2002;Nelson 1994;Schou 1998;Seymour 2000;Wahl 1997) (Analysis 3.5.1). The proportion of participants with at least 50% pain relief was 49% (553/1126) for ibuprofen 200 mg, and 10% (80/827) for placebo; the RB was 4.6 (3.7 to 5.6), and the NNT was 2.5 (2.3 to 2.8).…”
Section: Ibuprofen 200 Mg: (Analysis 35)mentioning
confidence: 99%
“…• Three studies using ibuprofen 100 mg reported the proportion of participants using rescue medication over 6 hours (Jain 1986;Schou 1998;. The weighted mean proportion was 38% (54/143) with ibuprofen and 64% (88/153) with placebo, giving an NNTp of 3.8 (2.7 to 6.5) (Analysis 2.2).…”
Section: Use Of Rescue Medicationmentioning
confidence: 99%
See 2 more Smart Citations