Analgesic Potential of Essential Oils

Sarmento-Neto, José F.; Nascimento, Lázaro Gomes do; Felipe, Cícero Francisco Bezerra; Sousa, Damião Pergentino de

doi:10.3390/molecules21010020

Cited by 66 publications

(51 citation statements)

References 168 publications

(229 reference statements)

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“…60,61 Lavandula angustifolia Mill is rich in essential oil and is especially indicated for headaches caused by fatigue and stress in the forms of both an extract and an essential oil for its sedative and antispastic properties. 62 It exerts a rebalancing action on the central nervous system, being simultaneously tonic and sedative. It calms anxiety, agitation, and nervousness; relieves headaches and disorders caused by stress; and helps reconcile sleep.…”

Section: Phytotherapy and Headachementioning

confidence: 99%

Nutrition and Phytotherapy: A Winning Combination Against Headache

Ferrara

2019

Int J Med Rev

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Introduction Headache is a pathological form of endemic character that prevents the performance of normal activities, both working and relational. It is difficult to consider both the multiple causes and the various factors competing in this event, due to the lack of objective parameters that allow the clear classification of the various types of headache. 1 Migraine, the scientific term in which headache is indicated, is classified in many categories and sub-categories considering not only the quality, intensity, and cyclicity of pain, but also the way it manifests itself. A primary headache is generally distinguished from hormonal or environmental causes, including migraine, tension headache, and cluster headache; a secondary headache is the main symptom of other disorders, such as allergies, sinusitis, hypertension, osteoarthritis, digestive difficulties; pain that manifests itself following the excessive intake of some substances such as coffee, alcohol, and drugs; pain resulting from a lack of substances such as sugars, or in particular physical conditions, physical exertion, stress, or environmental, excessive cold or altitude. 2-4 The main manifestation is pain that can be localized to the occipital region or diffused to the whole skull, pulsating or strongly intensive, excruciating, monolateral with involvement of the ocular region and the occipital area. 5 Periodicity also represents a characteristic of the headache in addition to different durations of pain. Often, there are well-defined associated symptoms, such as lacrimation and irritation of the conjunctiva, nasal congestion, eye swelling, or pupil contraction, found especially in cluster headaches. The warning symptoms of pathological onset, like irritability, fatigue, and intolerance to noise, are characteristic of migraine that can degenerate even into blurred vision, alteration of sensitivity, and disorders of consciousness found in the most severe cases of migraine with aura. 6 The presence of attacks is variable depending on whether it is an episodic, chronic, or recurrent headache, and the duration may vary from half an hour to 1 hour, on two or three consecutive days. 7 Today there is no specific treatment for headaches, and sufferers often resort to empirical methods or self-medication. The agents available for the treatment of headaches are few and often have side effects such as sedation and nausea, which weaken, even if temporarily, so they cannot be used continuously. 8-10 Food-Headache Relationship The use of proper nutrition to prevent and alleviate the symptoms of headache is a practice the origins of which are very old. Hippocrates knew well the relationship between the ingestion of some substances and the onset of migraine for which many foods can be the main cause due to the

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Section: Phytotherapy and Headachementioning

confidence: 99%

Nutrition and Phytotherapy: A Winning Combination Against Headache

Ferrara

2019

Int J Med Rev

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“…The compositions of the EOs are greatly influenced by diverse parameters involving time and season of harvesting of the plants, type of the plant organs and the corresponding family, geographical and climatic conditions, physiological age, developmental stage, nutritional status of the plants, post-harvest drying, plant storages, genetic diversity, extraction methods, elemental structure of the sampling area, physicochemical variables related to the respective soils and also stress during the growth or maturity (Tabanca et al, 2011;Raut and Karuppayil, 2014;Mohammadhosseini, 2015b, a;Nekoei and Mohammadhosseini, 2016). Some comprehensive reviews covering some important aspects, e.g., the status, preparation methods, biological activities, potential use and processing of the EOs (Radulovic et al, 2007;Bakkali et al, 2008;Nemeth and Bernath, 2008;Adorjan and Buchbauer, 2010;Rubiolo et al, 2010;Lang and Buchbauer, 2012;Shaaban et al, 2012;Tranchida et al, 2012;Oliveira et al, 2014;Raut and Karuppayil, 2014;Sivakumar and Bautista-Banos, 2014;Tongnuanchan and Benjakul, 2014;Xiao et al, 2014;Calo et al, 2015;Herman and Herman, 2015;Zeng et al, 2015;Sarmento-Neto et al, 2016) are available to date.…”

Section: Introductionmentioning

confidence: 99%

Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review

Mohammadhosseini

Sarker

Akbarzadeh

2017

Journal of Ethnopharmacology

163

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“…The results depicted that topical, administration of oil at both doses 1% and 2% significantly showed best activity at 90 and 120 minutes. The hot-plate method is considered to be selective for screening of the compound acting through the opioid receptor [26]. In various studies, the action of volatile oil is attributed to the combined effect of both their active and inactive compounds.…”

Section: Discussionmentioning

confidence: 99%

Topical Analgesic Activity of Essential Oil Extracted From Spharenthus Indicus (Asteraceae)

Padhan¹,

Sriballav²,

Arnabaditya³

2017

Asian J Pharm Clin Res

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Objective: The objective of this study was to evaluate the topical analgesic effects of essential oil extracted from Sphaeranthus indicus (Asteraceae). Methods:The essential oil was extracted from fresh flower of S. indicus. Topical ointment containing essential oil was investigated for analgesic activity in rat using hot-plate method. Diclofenac sodium gel was taken as standard drug. Result:The analgesic activity of topical preparation was observed in the early phase. The analgesic activity of topical preparation containing 2% S. indicus flower essential oil showed significant activity (11.5±0.34 and 11.83±0.40) comparative to standard drug diclofenac sodium (11.83±0.31 and 12.66±0.61) at 90 and 120 minutes of application of drug by hot-plate method (p<0.001). Conclusion:Hence, the study validates the traditional use of S. indicus to relive pain.

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Analgesic Potential of Essential Oils

Cited by 66 publications

References 168 publications

Nutrition and Phytotherapy: A Winning Combination Against Headache

Nutrition and Phytotherapy: A Winning Combination Against Headache

Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review

Topical Analgesic Activity of Essential Oil Extracted From Spharenthus Indicus (Asteraceae)

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