Análise de indivíduos com leucemia: limitações do sistema de vigilância de câncer

Moraes, Elisane Silveira; Sarpa, Marcia; Nogueira, Fernanda de Albuquerque Melo; Otero, Ubirani Barros; Carvalho, Flávia Nascimento de

doi:10.1590/1413-812320172210.18292017

Cited by 14 publications

(16 citation statements)

References 23 publications

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“…In another Brazilian study associating occupation profiles in patients with leukemia diagnosis, these data were found in only 52% of the medical files. 12 In this study similarities and discrepancies became apparent when confronted with other reports. Like other studies there was a predominance of males.…”

Section: Discussionsupporting

confidence: 54%

“…Like other studies there was a predominance of males. 2,12 Nevertheless, the white race did not match with people in this region of the country (IBGE). Another peculiarity in our sample was a predominance of people with higher education and income when compared to the rest of the Brazilian population, who have lower average schooling and lower salaries.…”

Section: Discussionmentioning

confidence: 99%

“…[8][9][10][11] In Brazil, cancer related to occupation remains little explored, with few available studies. [11][12][13] Thus, our objective is to describe the socio-demographic and occupational profile of the patients treated in tertiary hospitals located in the city of Rio de Janeiro, whose diagnoses of acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphocytic leukemia, chronic lymphocytic leukemia (CLL) and myelodysplastic syndromes were confirmed.…”

Section: Occupational Exposures Reported By Patients With Leukemia and Myelodysplastic Syndrome In Rio De Janeiro Brazil Introductionmentioning

confidence: 99%

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A exposição ocupacional relatada por pacientes com leucemia e com síndrome mielodisplásica e no Rio de Janeiro, Brasil

Ornellas

Alves

Rebelo

et al. 2019

BJHBS

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Introduction: Little is known about occupational agents andthe occurrence of leukemia and myelodysplastic syndromein Brazil. Objective: The aim of this study was to trace thesociodemographic and occupational profiles of patients withleukemia and myelodysplastic syndrome in two hospitals inthe city of Rio de Janeiro, Brazil. Methods: We carried out astudy of 229 cases from the period 2000 to 2006. Interviewswere conducted with patients to obtain information onfamily history, lifestyle risk factors, occupational history,residential history, and occupational and non-occupationalexposures by using a structured questionnaire. The frequencyand duration of occupational activities related to exposureamong participants were estimated. Each individual’s levelof exposure was classified as low, moderate, high or veryhigh. Results: The main exposures observed were to chemicalcleaning and disinfectant products, followed by gasolineand lubricating oil. Most of the exposures occurred at lowfrequencies. However, for benzene, solvents, thinners, andcoal combustion, the highest prevalence was observed formoderate exposures. Furthermore, it was observed that theexposure patterns of substances varied for each group, suggestingthat the intensity of exposure was determined byspecific types of substances. Conclusion: The monitoring ofexposure in occupations that deal with solvents is critical, inorder to reduce the incidence of leukemia. Since occupation isa preventable risk factor, strategies for primary prevention andhealth promotion in the workplace should be a top priorityin cancer prevention policies in Brazil.Keywords: Leukemia; Occupational Health, Myelodysplasticsyndromes, Epidemiology.

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Section: Discussionsupporting

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Occupational Exposures Reported By Patients With Leukemia and Myelodysplastic Syndrome In Rio De Janeiro Brazil Introductionmentioning

confidence: 99%

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A exposição ocupacional relatada por pacientes com leucemia e com síndrome mielodisplásica e no Rio de Janeiro, Brasil

Ornellas

Alves

Rebelo

et al. 2019

BJHBS

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“…Some studies have reported report leukemia incidences in this group cases in several Brazilian regions, although encompassing agricultural, hunting and fishing workers as a single group (Moraes et al, 2017). In addition, incomplete occupational information in Brazilian cancer hospital records is a reality, which directly reflects surveillance actions and associations between occupational, environmental and occupational exposure (Moraes et al, 2017), thus impeding further analyses of benzene-exposure scenarios concerning Brazilian fishers.…”

Section: Discussionmentioning

confidence: 99%

Vulnerability of small-scale fishers to benzene exposure and the current knowledge gap on benzene-exposure in Brazilian fishers

Hauser‐Davis

2019

PeerJ

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Fishers are a particularly vulnerable population, chronically exposed to many stresses, injuries and health conditions directly linked to their fishing activities. This includes benzene exposure through gasoline and diesel exhaust fumes. Benzene is a known carcinogen, and has been assessed in many worker groups, but reports on fisher benzene exposure are extremely scarce in the literature. This paper discusses benzene exposure in small-scale fishers and reflects on the current knowledge gap on benzene-exposure in Brazilian fishers.

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“…As SMD compreendem um grupo de doenças clonais manifestadas por citopenia periférica associada à hiperplasia medular e alto risco de transformação para Leucemia Mieloide Aguda (LMA) (Rozovski, et al, 2015;Leisch, et al, 2017;Moncharmont, et al, 2019). As leucemias, grupo de neoplasias malignas do tecido hematopoiético, sãoclassificadas em agudas e crônicas, e em mieloide ou linfoide (Moraes, et al, 2017). As leucemias agudas são mais agressivas, com curto tempo de instalação e se caracterizam pelo predomínio de blastos no sangue periférico e na medula óssea, uma vez que a célula leucêmica perde a capacidade de diferenciação (Lamego, et al,2010;Moraes, et al, 2017).As leucemias crônicas, de instalação insidiosa, preservam certa capacidade de diferenciação celular (morfológica), mas não funcional, com hiperproliferação de determinada linhagem celular, a depender da doença (Yamamoto & Figueiredo, 2005;Hamerschlak, 2008).…”

Section: Introductionunclassified

Aloimunização eritrocitária em pacientes politransfundidos com doenças onco-hematológicas: Uma revisão de literatura

Ramos

2021

RSD

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O objetivo desta revisão de literatura foi avaliar quais são as doenças onco-hematológicas mais frequentes em pacientes politransfundidos aloimunizados, determinar quais são os antígenos eritrocitários e os aloanticorpos antieritrocitários mais comuns detectados no perfil populacional do estudo, assim como identificar medidas adequadas a serem tomadas a fim de minimizar as taxas de aloimunização nesta população dependente de transfusão. Foram utilizados critérios de elegibilidade bem delineados e a busca ocorreu na base de dados bibliográfica eletrônica Medical Literature Analysis and Retrieval System Online (MEDLINE). A partir dos critérios utilizados foram incluídos 10 artigos para compor esta revisão.Verificou-seque a doença onco-hematológica mais prevalente na população estudada foi a Síndrome Mielodisplásica e os aloanticorpos detectados com maior frequência foram os associados aos sistemas Rh, Kell, MNS e Kidd. Todos os trabalhos apontaram a fenotipagem eritrocitária extensa como forma de minimizar as taxas de aloimunização entre os pacientes com neoplasias hematológicas, assim como reduzir os riscos de ocorrência de reações hemolíticas transfusionais. Portanto, a realização da fenotipagem e genotipagem para a identificação de outros sistemas além do ABO/Rh, principalmente para os pacientes cronicamente transfundidos e que apresentam Síndrome Mielodisplásica, pode minimizar o risco de aloimunização e suas consequências com reflexos positivos na segurança e eficácia da terapia transfusional.

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Análise de indivíduos com leucemia: limitações do sistema de vigilância de câncer

Cited by 14 publications

References 23 publications

A exposição ocupacional relatada por pacientes com leucemia e com síndrome mielodisplásica e no Rio de Janeiro, Brasil

A exposição ocupacional relatada por pacientes com leucemia e com síndrome mielodisplásica e no Rio de Janeiro, Brasil

Vulnerability of small-scale fishers to benzene exposure and the current knowledge gap on benzene-exposure in Brazilian fishers

Aloimunização eritrocitária em pacientes politransfundidos com doenças onco-hematológicas: Uma revisão de literatura

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