Análise do mesilato de imatinibe em plasma empregando a eletroforese capilar

Ajimura, Tatiana Okura

doi:10.11606/d.60.2010.tde-01122010-135234

Cited by 3 publications

(5 citation statements)

References 82 publications

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“…[10] lineshapes of the πΣ invariant mass spectra integrated over neutron angles are presented but in Ref. [9] lineshapes limited to θ n = 0 • are given by these authors, which exhibit similar peaks to the integrated ones. Since these peaks provide the basis of their argument with regard to the Λ(1405) resonance position, first we want to clarify where this conspicuous difference comes from.…”

Section: Resultsmentioning

confidence: 83%

“…5 and 6 where the Jülich meson-exchange [17,18] and the Oset-Ramos chiral interaction [12,13] are used for generating theKN − πΣ amplitude, respectively. We fixed the K − beam momentum to p K − = 600 MeV/c and the neutron angle to θ n = 0 • , considering the kinematics of the J-PARC experiment [9] where the neutron is planned to be detected at forward angle. Taking a glance at the figures, one immediately finds that no clear peaks are seen below the nK − p threshold (M πΣ ≃1432 MeV) for both the Jülich and the Oset-Ramos potentials.…”

Section: Resultsmentioning

confidence: 99%

“…Our study is motivated by a corresponding proposal submitted to the J-PARC 50-GeV proton synchrotron. This proposal aims at a spectroscopic study of hyperon resonances below thē KN threshold via the (K − , n) reaction on a deuteron target [9]. The primary goal of the experiment is to study the position and width of the Λ(1405) resonance produced in theKN → πΣ channel.…”

Section: Introductionmentioning

confidence: 99%

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Faddeev Calculation of the K⁻d →πΣn Reaction in the Λ(1405) Resonance Region

Miyagawa¹,

Haidenbauer²

2017

Proceedings of the 12th International Conference on Hypernuclear and Strange Particle Physics (HYP2015)

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The set of coupled Faddeev equations for theKNN − πΣN system is derived and the reaction K − d → πΣn, for which measurements are currently performed at J-PARC, is analyzed based on it. The present results in which the transition to the πΣN system is treated perturbatively show a peak in the Λ(1405) resonance region, but no clear enhancement above theKN threshold as suggested by the preliminary data of the J-PARC experiment. We point out that the observed enhancement originates from the quasi-free scattering between the incident K − and one of the nucleons in the deuteron, and we argue for the necessity of including full πΣN three-body processes in a realistic calculation.

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Section: Resultsmentioning

confidence: 83%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Faddeev Calculation of the K⁻d →πΣn Reaction in the Λ(1405) Resonance Region

Miyagawa¹,

Haidenbauer²

2017

Proceedings of the 12th International Conference on Hypernuclear and Strange Particle Physics (HYP2015)

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“…Imatinib absorbance showed peaks at 200 nm and from 250 to 280 nm, the same range used to qualify and quantify DNA/RNA samples (230, 260 and 280 nm). Another study that also analyzed the absorbance of this drug, observed a similar absorption spectrum, with detection at 200, 250 and 270 nm [17]. Hanna and Gairani [18] also analyzed the absorption spectrum of Imatinib® mesylate and identified that the highest absorbance point of the drug was between 260 and 270 nm.…”

Section: Discussionmentioning

confidence: 81%

Analysis of the qPCR Assay Efficacy as Molecular Diagnostic in Patients with Chemotherapy and/or Antibiotic Therapy

Moreira¹,

Agostinho

2021

Braz. arch. biol. technol.

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High sensitivity of qPCR assay can be compromised by the presence of PCR inhibitors in samples analyzed. The aim of this study was to analyze the RT-qPCR assay efficiency considering the RNA quality/quantity and the presence of PCR inhibitors in patients with chemotherapy and/or antibiotic therapy. We analyzed 60 samples using RT-qPCR from individuals suspected of leukemia and 44 samples were quantified by fluorimetry and spectrophotometry. The efficiency of the RT-qPCR assay was evaluated comparing the threshold cycle (Ct) from tested samples and the standard curve. The 260/280 and 260/230 ratios, the presence of PCR inhibitors and the amount of sample (ng) used in the RT-qPCR reaction can be associated with 56.8% (R²=0.56, p<0.05) in the Ct obtained. The decrease of the RT-qPCR efficiency can be explained in 42,8% due to the variation of the 260/280 ratio (R²=0.42,p<0.05). The presence of antibiotics in the blood sample can be associated in 11.3% with the variability of 260/280 ratio (R²=0.11,p<0.05). Presence of chemotherapeutic drugs in the blood sample was not correlated with Ct variation (p=0.17). The spectrophotometer determines a RNA quantification with 2.2 times higher than the fluorimeter (t=2.2, p=0,03) and this difference is correlated with the 260/280 ratio (R²=0.36, p<0.05). Samples with low purity had a reduction in the qPCR efficiency, although we did not observe false results.

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“…Our analysis strategy can be used to understand dark photon decaying to DM in similar COHERENT type set-ups with timing measurements, e.g. JSNS 2 [38]. The upcoming data from the ongoing COHERENT and the future runs of the COHERENT and JSNS 2 experiments would be able to investigate a large region of parameter space in this type of DM models which can be compared with the reach projected by the proposed LDMX and DUNE experiments to probe similar DM scenarios.…”

Section: Discussionmentioning

confidence: 98%

Dark Matter Signals from Timing Spectra at Neutrino Experiments

et al. 2020

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We propose a novel strategy to search for new physics in timing spectra, envisioning the situation in which a new particle comes from the decay of its heavier partner with a finite particle width.The timing distribution of events induced by the dark matter particle scattering at the detector may populate in a relatively narrow range, forming a "resonance-like" shape. Due to this structural feature, the signal may be isolated from the backgrounds, in particular when the backgrounds are uniformly distributed in energy and time. For proof of the principle, we investigate the discovery potential for dark matter from the decay of a dark photon in the COHERENT experiment, and show the exciting prospects for exploring the associated parameter space with this experiment.We analyze the existing CsI detector data with a timing cut and an energy cut, and find, for the first time, an excess in the timing distribution which can be explained by such dark matter. We compare the sensitivity to the kinetic mixing parameter ( ) for current and future COHERENT experiments with the projected limits from LDMX and DUNE. *

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Análise do mesilato de imatinibe em plasma empregando a eletroforese capilar

Cited by 3 publications

References 82 publications

Faddeev Calculation of the K⁻d →πΣn Reaction in the Λ(1405) Resonance Region

Faddeev Calculation of the K⁻d →πΣn Reaction in the Λ(1405) Resonance Region

Analysis of the qPCR Assay Efficacy as Molecular Diagnostic in Patients with Chemotherapy and/or Antibiotic Therapy

Dark Matter Signals from Timing Spectra at Neutrino Experiments

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Análise do mesilato de imatinibe em plasma empregando a eletroforese capilar

Cited by 3 publications

References 82 publications

Faddeev Calculation of the K−d →πΣn Reaction in the Λ(1405) Resonance Region

Faddeev Calculation of the K−d →πΣn Reaction in the Λ(1405) Resonance Region

Analysis of the qPCR Assay Efficacy as Molecular Diagnostic in Patients with Chemotherapy and/or Antibiotic Therapy

Dark Matter Signals from Timing Spectra at Neutrino Experiments

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Product

Resources

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Faddeev Calculation of the K⁻d →πΣn Reaction in the Λ(1405) Resonance Region

Faddeev Calculation of the K⁻d →πΣn Reaction in the Λ(1405) Resonance Region