Blockchain is a distributed ledger technology that ensures the security and transparency of data, guaranteeing that they cannot be altered. Its application in the peer review of scientific papers can contribute to improving the integrity, transparency, and efficiency of the process, mitigating issues of manipulation and fraud. This work analyzes the contributions of various research studies that address the use of blockchain technology in peer review. The study is a systematic literature review (SLR) in which the PRISMA methodology was applied. Fifty primary studies were identified through searches in databases such as Scopus, Science Direct, IEEE Xplore, and ACM. The analyzed research reveals innovative approaches, such as decentralized solutions, smart contracts, and token economy, to address challenges like biases, transparency, and speed in the review process. It is concluded that the use of blockchain in peer review processes is still emerging and has not yet been widely adopted globally. However, studies addressing this topic focus on its potential to improve transparency and trust in the process, offer incentives and rewards to reviewers and authors, enhance the quality and fairness of evaluations, and strengthen the security and privacy of the data involved.