Entrepreneurial mental readiness is essential for students to have before starting a business. Given the importance of mental readiness in entrepreneurship, the researchers arranged prophetic entrepreneurship to increase the students' mental readiness for entrepreneurship at UIN Antasari Banjarmasin. Samples were taken randomly. After the screening process, 82 research subjects were obtained, then divided into experimental and control groups consisting of 41 people. The design used in this study was an untreated control group design with pretest and post-test. Data analysis used Paired Sample T-Test to determine the effect of prophetic entrepreneurship on the experimental and control groups before and after the training. The initial assessment results show that students have low entrepreneurial mental readiness. However, training prophetic entrepreneurship can improve student entrepreneurship mental readiness with an effectiveness of 57%.