This research was aimed to find out determine the effect of liquidity ratios, profitability ratios, leverage ratios, and operating cash flow in predicting financial distress in manufacturing companies listed on the Indonesia Stock Exchange (2015-2018). Liquidity ratio, profitability ratio, leverage ratio, and operating cash flow as independent variables, while financial distress as independent variables The object used in manufacturing companies, the sample of 105 companies. Logistic regression analysis was used for the technique analysis of the data. The results showed that the ratio of liquidity and operating cash flow did not influence in predicting financial distress while the other two variables namely profitability ratios and leverage ratios had a very strong influence in predicting financial distress.