We read the publication on "Analisis temporal y espacial de las muertes infantiles por microcefalia en Argentina (1998-2012)" with a great interest [1]. Dipierri and Bronberg concluded that "Esta distribución se relaciona con la mayor pobreza y consanguinidad del norte de la Argentina, factores sinérgicos predisponentes de la ocurrencia de malformaciones congénitas en general y de microcefalia en particular [1] ." Indeed, the microcephaly becomes the new global issue when the Zika virus emerges. The possible relationship between microcephaly and Zika virus infection is shown in some settings but the opposite findings are generally reported from others. The present report from Argentina might not support the correlation. We would like to share our observation in Indochina where the Zika virus infection is also common. Until present, despite several months of disease emergence, there is still no scientific evidence to confirm the relationship between infection and microcephaly in out setting. Indeed, the asymptomatic nature of Zika virus infection is common in Indochina [2-3] and the lack of occurrence of Zika virus related microcephaly [4] might support the finding in the present study by Dipierri and Bronberg [1] .