In a context of climate change and declining water resources, knowledge of low flow is essential. Present study deals with the spatial and temporal evolution of the streams low flow in Sassandra river. In the study, 12 stations of the Sassandra sub-basins (Sassandra, N'zo, Lobo, and Davo) were selected according to the availability and quality of long-term data. Annual, monthly and daily low flow data from twelve hydrological stations of the Sassandra watershed were used and cover the period from 1970 to 2015. The methodology used is concerned with extracting the low flow data and analyzing and evaluating the trends (Mann-Kendall) and change-point (cumulate sum) of low flow data. Statistical tests are applied to the mean and variance of the low-flow series. The results of the statistical tests show more trends and change points on the mean than on the variance. Significant trends show an increase in low flow waters. The significant change point detected by the cumulative sums test generally occurs between 1990-2007. In addition, tributaries are more affected by significant trends and change point detection than Sassandra river.