Analyses of the Essential Oil from Bunium persicum Fruit and its Antioxidant Constituents

Nickavar, Bahman; Adeli, Abrisham; Nickavar, Azar

doi:10.5650/jos.ess13168

Cited by 22 publications

(12 citation statements)

References 18 publications

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“…超声萃取 [23] 和加速溶剂萃取(ASE)等 [24] 常用来提取土壤、沉积物、空气颗粒物和食品等固体样品, 可有效提取样品中中度疏水性至强疏水性的化合物 [25] , 具有节省溶剂、流程快速、基质影响小和重现性好等优点. 近年来, 运用EDA技术对生物样品(如哺乳动物血液 [20,26] 、动物器官组织 [27,28] 和植物提取液 [29,30] )的研究逐渐增多. Suzuki等 [27] 基于海豹肝脏建立了生物组织样品的丙酮-正己烷萃取方法, 再以硫酸钠-硫酸硅胶柱进行样品净化, 该方法对1,2,3,7,8-PeCDD、PCB126和p,p′-DDE的回收率能达到79%~110%, 可有效应用于海豹、鸬鹚、浣熊和江豚等动物的脂肪和肝脏样品的前处理工作. 加速膜辅助清理(accelerated membrane-assisted cleanup, AMAC)技术适用于富含脂质的生物样品的前处理 [31,32] , 能够在除去生物样品中90%脂质的…”

Section: 常规样品提取方法unclassified

Effect-directed analysis in environment research: current status and future challenges

Liu

Shi

et al. 2018

Sci. Sin.-Chim

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The increasingly severe chemical pollution poses treats to environmental and human health. Effect-directed analysis (EDA), based on a combination of biotesting, sample fractionation and chemical identification and quantification, is a powerful tool for identification of environmental toxicants in complex chemical mixtures in the environment. This review summarized recent advances in EDA, including sample extraction and fractionation, biological tests and chemical identification. The application of high throughput screening in EDA was discussed and challenges in future studies were also identified.

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Section: 常规样品提取方法unclassified

Effect-directed analysis in environment research: current status and future challenges

Liu

Shi

et al. 2018

Sci. Sin.-Chim

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“…Bunium Persicum which belongs to the Apiaceae family and is generally known in Iran as 'Zireh Siah' has always been used in traditional Iranian medicine for specific disorders [19,20]. The main constituents of BP, which have been demonstrated in recent studies, are cumin aldehyde, caffeic acid, p-coumaric acid, gamma-terpinene, and p-cymene, cuminal, flavonoids (such as quercetin and kaempferol) and a high level of polyphenols compound [21][22][23][24][25]. The reported effects of cumin aldehyde, as one of the most studied agent, include the inhibition of aldose reductase and r-Glucosidase, the insulinotropic, and b cellprotective action, anti-obesity, and liver protective effect [26][27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Metabolic and clinical responses to Bunium Persicum (black caraway) supplementation in overweight and obese patients with type 2 diabetes: a double-blind, randomized placebo-controlled clinical trial

et al. 2020

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Background: Diabetes mellitus is the most common metabolic disorder worldwide. We aimed to determine the metabolic and clinical responses to Bunium Persicum (Black Caraway) supplementation in overweight and obese patients with T2DM. Methods: Participant recruitment took place in the diabetic clinic of Bu-Ali hospital in Zahedan. Due to the eligibility criteria, 60 participants were randomly placed into two groups, namely placebo (n = 30) and BP (n = 30). The supplementation was considered one 1000 mg capsule 2 times /day BP by meals (lunch and dinner) for 8 weeks. Physical activity levels, dietary intakes, anthropometric measurements [weight, height, and waist circumference], glycemic indices [fasting blood glucose (FBG) and insulin (FBI)], blood lipids [triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c)], and serum nesfatin-1 level were determined. Homeostasis model assessment-insulin resistance (HOMA-IR), Quantitative insulin sensitivity checks index (QUICKI), and Body Mass Index (BMI) were computed. Results: In comparison with placebo, BP significantly decreased FBG, HOMA-IR, and BMI (P < 0.05). The differences in the FBI, QUICKI, TG, TC, LDL, HDL, WC, and Nesfatin-1 were not significant (P > 0.05). Conclusion: BP supplementation improved serum glucose indices and BMI among overweight and obese T2DM patients. Further trials are needed to confirm results.

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“…Furthermore, it may serve as a dietary source of natural antioxidants for health improvement and may be used as a natural antioxidative food additive to increase food quality and stability (19) . The known main constituents of BP have been demonstrated as gamma-terpinene, p-cymene, cuminal and cumin aldehyde (20,21) .…”

Section: Introductionmentioning

confidence: 99%

The effects of Bunium Persicum (Black Caraway) supplementation on glycemic indices, lipid profiles and serum levels of nesfatin-1 in overweight and obese patients with type 2 diabetes: a double-blind randomized placebo-controlled clinical trial

Jafari-Maskouni¹,

Shahraki²,

Daneshi-Maskooni³

et al. 2020

Preprint

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Background: Diabetes mellitus is the most common metabolic disorder worldwide. Our aim was to determine the effects of bunium persicum (BP) on serum glucose indices, lipid profile, and nesfatin-1 levels among overweight or obese T2DM patients.Methods: The place of participant recruitment was the diabetic clinic of Bu-Ali hospital in Zahedan. Based on the eligibility criteria, 60 participants were randomly divided into two groups as BP (n=30) or placebo (n=30). The supplementation was one 1000 mg capsules 2 times/day BP with launch and dinner for 8 weeks. Bodyweight, Waist circumference, serum nesfatin-1, fasting blood sugar (FBS), insulin (FBI), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were measured. Quantitative insulin sensitivity checks index (QUICKI), homeostasis model assessment-insulin resistance (HOMA-IR) and Body Mass Index (BMI) were also calculated.Results: In comparison with placebo, PB significantly increased QUICKI and decreased FBS, HOMA-IR, BMI and WC (P<0.05). At the end of the study after adjustment for confounders, the changes were similar (P<0.05) with an exception for QUICKI which had a trend (P=0.054) and WC (P > 0.05). The differences in the FBI, TG, TC, LDL, HDL and Nesfatin-1 were not significant (P>0.05).Conclusion: PB supplement improved serum glucose indices and decreased BMI among overweight or obese T2DM patients; though, further trials are suggested to confirm results.

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Analyses of the Essential Oil from Bunium persicum Fruit and its Antioxidant Constituents

Cited by 22 publications

References 18 publications

Effect-directed analysis in environment research: current status and future challenges

Effect-directed analysis in environment research: current status and future challenges

Metabolic and clinical responses to Bunium Persicum (black caraway) supplementation in overweight and obese patients with type 2 diabetes: a double-blind, randomized placebo-controlled clinical trial

The effects of Bunium Persicum (Black Caraway) supplementation on glycemic indices, lipid profiles and serum levels of nesfatin-1 in overweight and obese patients with type 2 diabetes: a double-blind randomized placebo-controlled clinical trial

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