Analysis and comparison of Radix Glycyrrhizae (licorice) from Europe and China by capillary-zone electrophoresis (CZE)

Rauchensteiner, Florian; Matsumura, Yukihiko; Yamamoto, Yutaka; Yamaji, Seiichi; Tani, Tohru

doi:10.1016/j.jpba.2005.01.038

Cited by 85 publications

(43 citation statements)

References 19 publications

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“…by similarity analysis or principal component analysis) were discussed in several publications [12,[127][128][129][130]. In Table 5, recent examples for quality control of medicinal plants by CE-fingerprints are compiled, including respective separation conditions [131][132][133][134][135][136][137][138]. In some of the reports, the simultaneous quantitative determination of individual compounds (e.g.…”

Section: Fingerprintingmentioning

confidence: 99%

Quality control of herbal medicines by capillary electrophoresis: Potential, requirements and applications

Ganzera

2008

Electrophoresis

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Herbal preparations, particularly those from traditional Chinese or Indian medicine, are becoming increasingly popular in Europe and the USA. Their application is often based on long-term historic use rather than on scientific evidences; thus, analytical tools to assure their efficacy, safety and consistency are in great demand. This review evaluates the importance of CE for quality control of herbal medicinal products during the last five years. After briefly describing the general characteristics of natural products analysis by CE, numerous applications on medicinal plants or herbal products are summarized. These examples not only reflect the enormous variability of CE with respect to buffer systems and detection modes employed, but also indicate an increasing importance of this separation technique for quality control purposes compared with more established ones such as HPLC.

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Section: Fingerprintingmentioning

confidence: 99%

Quality control of herbal medicines by capillary electrophoresis: Potential, requirements and applications

Ganzera

2008

Electrophoresis

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“…Up to now, various analytical methods [16] have been reported by using thin-layer chromatography [17] and capillary electrophoresis [18]. In addition, several HPLC methods were also used to investigate the chemical constituents of Glycyrrhiza species [19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Identification and simultaneous determination of glycyrrhizin, formononetin, glycyrrhetinic acid, liquiritin, isoliquiritigenin, and licochalcone A in licorice by LC-MS/MS

Xie¹,

Zhang²,

Wang³

et al. 2014

Acta Chromatographica

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Summary.A new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for simultaneous determination of glycyrrhizin, formononetin, glycyrrhetinic acid, liquiritin, isoliquiritigenin, and licochalcone A in licorice. An Eclipse Plus C 18 column (I.D. 4.6 × 100 mm, 3.5 μm particle size; Agilent) was used in the analysis. Electrospray ionization (ESI)-tandem interface in the negative mode was performed, and multiple reaction monitoring (MRM) was employed with the precursor multiple reaction monitoring production combination for the determination of six analytes. The average recoveries ranged from 98.30% to 100.13% with relative standard deviations (RSDs) ≤1.95%, and limits of detection (LODs) ranged from 2.1 to 3.6 pg. The applicability of this analytical approach was confirmed by the successful analysis of six samples. The results indicated that the established method was validated, sensitive, and reliable for the determination of six analytes in licorice.

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“…The ordinary botanical sources of licorice are Glycyrrhiza glabra L., which is geographically distributed from Southern Europe to Western China, and G. uralensis Fisch, found from Central Asia to Eastern China (Rauchensteiner et al, 2005). The use level of licorice is high due to many pharmacological properties, whereas licorice sources are limited regions in the world.…”

Section: Introductionmentioning

confidence: 99%

Production of Glycyrrhizin in Callus Cultures of Licorice

Wongwicha

Tanaka

Shoyama

et al. 2008

Zeitschrift Für Naturforschung C

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Licorice plants, Glycyrrhiza glabra, G. uralensis, and G. inflata, were investigated for callus induction using Murashige and Skoog (MS) medium combined with auxins and cytokinins. After 4 weeks of culture, 33Ð100% of leaf or stem explants formed calli. Maximum of shoot induction from callus cultures was achieved by G. inflata stem explants cultured on MS medium supplemented with 1 mg/l α-naphthaleneacetic acid (NAA) and 0.5 mg/l 6-benzyladenine (BA) (67%) which also gave maximum shoot formation per explant (two shoots per explant). These results indicated that all three Glycyrrhiza species regenerated shoots from callus cultures on MS medium combined with NAA and BA or only thidiazuron (TDZ; 0.1 and 0.5 mg/l). Glycyrrhizin contents of G. uralensis calli induced using MS medium in combination with NAA and BA [(27.60

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Analysis and comparison of Radix Glycyrrhizae (licorice) from Europe and China by capillary-zone electrophoresis (CZE)

Cited by 85 publications

References 19 publications

Quality control of herbal medicines by capillary electrophoresis: Potential, requirements and applications

Quality control of herbal medicines by capillary electrophoresis: Potential, requirements and applications

Identification and simultaneous determination of glycyrrhizin, formononetin, glycyrrhetinic acid, liquiritin, isoliquiritigenin, and licochalcone A in licorice by LC-MS/MS

Production of Glycyrrhizin in Callus Cultures of Licorice

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